Aasdhppt Gene Summary [Rat]
Predicted to enable holo-[acyl-carrier-protein] synthase activity and magnesium ion binding activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid and protein maturation. Predicted to act upstream of with a positive effect on 10-formyltetrahydrofolate catabolic process. Predicted to be active in cytosol. Orthologous to human AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Aasdhppt |
| Official Name | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Source:RGD Symbol;Acc:1311360] |
| Ensembl ID | ENSRNOG00000005795 |
| Bio databases IDs | |
| Aliases | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| Synonyms | 2010309J24Rik, 2810407B07Rik, AASD-PPT, ACPS, AD010, aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, CGI-80, LYS2, LYS5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Aasdhppt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- L-aminoadipate-semialdehyde dehydrogenase
- enzyme
- protein binding
- holo-[acyl-carrier-protein] synthase
- magnesium ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Aasdhppt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pantothenate metabolic process
- 10-formyltetrahydrofolate catabolic process
- protein maturation
- lysine biosynthetic process via aminoadipic acid
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- protein binding
- holo-[acyl-carrier-protein] synthase activity