dPCR LNA Mutation Assays

For detecting specific DNA sequence mutations related to cancer and oncogenesis

  • Duplex assay design detects mutated and wild-type sequences
  • Choice of FAM + HEX or Atto 550 + ROX fluorescent dye combinations
  • LNA-enhanced primers and probes increase assay specificity and sensitivity
  • Wet-lab tested dPCR assays available for more than 200 targets
  • Suitable for use with circulating tumor DNA, liquid biopsy, FFPE and other tissue samples
  • Intended for use with QIAcuity Probe PCR Kits

Product

Product List20 products

GeneGlobe ID: DMH0000285 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 520 Human
AA Mutation: p.G12V
Nucleotide Mutation: c.35G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000024 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 1135364 Human
AA Mutation: p.Q61H
Nucleotide Mutation: c.183A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000331 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 528 Human
AA Mutation: p.G13S
Nucleotide Mutation: c.37G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000195 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 527 Human
AA Mutation: p.G13C
Nucleotide Mutation: c.37G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000286 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 521 Human
AA Mutation: p.G12D
Nucleotide Mutation: c.35G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000289 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 532 Human
AA Mutation: p.G13D
Nucleotide Mutation: c.38G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000309 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 516 Human
AA Mutation: p.G12C
Nucleotide Mutation: c.34G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000519 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 517 Human
AA Mutation: p.G12S
Nucleotide Mutation: c.34G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000290 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 1159597 Human
AA Mutation: p.Q61K
Nucleotide Mutation: c.181C>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0001055 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 522 Human
AA Mutation: p.G12A
Nucleotide Mutation: c.35G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000332 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 529 Human
AA Mutation: p.G13R
Nucleotide Mutation: c.37G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000198 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 553 Human
AA Mutation: p.Q61L
Nucleotide Mutation: c.182A>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000334 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 533 Human
AA Mutation: p.G13A
Nucleotide Mutation: c.38G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000525 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 531 Human
AA Mutation: p.G13D
Nucleotide Mutation: c.38_39delinsAT
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000022 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 551 Human
AA Mutation: p.Q61P
Nucleotide Mutation: c.182A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000025 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 1146992 Human
AA Mutation: p.Q61H
Nucleotide Mutation: c.183A>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000044 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 550 Human
AA Mutation: p.Q61E
Nucleotide Mutation: c.181C>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000284 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 518 Human
AA Mutation: p.G12R
Nucleotide Mutation: c.34G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000023 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 552 Human
AA Mutation: p.Q61R
Nucleotide Mutation: c.182A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000527 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay KRAS 534 Human
AA Mutation: p.G13V
Nucleotide Mutation: c.38G>T
dPCR wet-lab validated
Product Specification
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Resources

Instrument User Manuals (1)
Quick-Start Protocols (1)
Safety Data Sheets (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Certificates of Analysis (1)