Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Anaplastic Glial Tumors
PTEN, TP53 (p53)
Astrocytomas
BRAF, CHEK2 (RAD53), FGFR1, IDH1, KRAS, PTPN11, TP53 (p53)
Ependymomas
H3-3A, NF2
Glioblastomas
APC, BCOR, BRAF, CREBBP (CBP), EGFR (ERBB1), H3-3A, IDH1, MLH1, MSH2, MTOR, NRAS, PIK3CA (p110-alpha), PMS2, PMS2CL, PTEN, TERT, TP53 (p53)
Gliomas
ACVR1 (ALK2), BRCA2, CHEK2 (RAD53), FGFR1, H3-3A, PIK3CA (p110-alpha), PTEN, TP53 (p53)
High-Grade Gliomas
BRAF, EGFR (ERBB1), IDH1
Medulloblastomas
BRCA2, CREBBP (CBP), FGFR1, IDH1, MSH2, NRAS, PIK3CA (p110-alpha), PTCH2, SUFU, TP53 (p53)
Meningiomas
NF2, PTEN
Oligodendrogliomas
IDH1, MSH2, TERT