Target List
Embryonic Stem Cell (ESC) Specific Genes
Embryonic Stem Cell Markers
ALPL, GDF3 (VGR-2), TDGF1, TERT
Chromatin Modification Enzymes & Remodeling Factors
CHD1, CHD7, KAT5
Transcriptional Regulation
CNOT3, NR0B1, PAF1, TRIM28
Transcription Factors
ESRRB, KLF4, LIN28A, MYC, NANOG, POU5F1 (OCT4), PRDM14, SALL4, SMAD1 (MADH1), SMAD2 (MADH2), SMAD3 (MADH3), SOX2, STAT3, TBX3, TCF3, THAP11, UTF1, ZFX
Pluripotency
AICDA (AID), AICDA (AID), CCNA2, CDC42, CDK1, DPPA2, DPPA3, DPPA4, DPPA5, FGF2 (BFGF), HSPA9, MYBL2, NR5A2, NR6A1, OTX2, RIF1, SCN1A, SOX15, TCL1A, ZFP42
Induced Pluripotent Stem Cell Enhancers
AICDA (AID), AICDA (AID), KLF4, LIN28A, MYC, NANOG, POU5F1 (OCT4), SOX2, UTF1
Germ Layers
Ectoderm
EN2, FGF5, MEIS1, NCAM1, PAX6
Mesoderm
DES, HAND1, MESP1, MIXL1, MYOD1, TBXT (Brachyury)
Endoderm
GATA1, GATA6, GSC, HNF4A, SOX17, SOX7
Progenitors & Multi-Potent Stem Cells
Neural Progenitors
GFAP, NES, OLIG2, SOX3
Cardiac Progenitors
ISL1, NKX2-5
Early Smooth Muscle Cells
ACTA2 (α-SMA), TAGLN
Hematopoietic Stem Cells & Early Endothelial Cells
ETV2, FLII, GATA2, TAL1, TEK (TIE-2, TIE2)
Mesenchymal Stem Cells
CD44, ENG (EVI-1), NT5E, THY1
Preadipocytes
ALB, TAT