Details
| Type | Immunoglobulin Constant Gene |
| Official Symbol | Igkc |
| Official Name | immunoglobulin kappa constant [Source:MGI Symbol;Acc:MGI:96495] |
| Ensembl ID | ENSMUSG00000076609 |
| Bio databases IDs | |
| Aliases | immunoglobulin kappa constant |
| Species | Mouse, Mus musculus |
Pathways
Biological processes and signaling networks where the Igkc gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- Allograft Rejection Signaling
- Autoimmune Thyroid Disease Signaling
- B Cell Receptor Signaling
- Communication between Innate and Adaptive Immune Cells
- Dendritic Cell Maturation
- FcγRIIB Signaling in B Lymphocytes
- IL-12 Signaling and Production in Macrophages
- IL-15 Signaling
- p70S6K Signaling
- Phagosome Formation
- PI3K Signaling in B Lymphocytes
- Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis
- Role of NFAT in Regulation of the Immune Response
- Systemic Lupus Erythematosus Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- abnormal B cell differentiation
- abnormal B cell number
- abnormal Peyer's patch germinal center morphology
- abnormal Peyer's patch morphology
- abnormal humoral immune response
- abnormal immunoglobulin level
- abnormal immunoglobulin light chain V-J recombination
- decreased immature B cell number
- decreased mature B cell number
- increased immature B cell number
- increased mature B cell number
- increased pre-B cell number
- spleen hypoplasia