Details
| Type | Protein Coding |
| Official Symbol | Pms2 |
| Official Name | PMS1 homolog2, mismatch repair system component [Source:MGI Symbol;Acc:MGI:104288] |
| Ensembl ID | ENSMUSG00000079109 |
| Bio databases IDs | |
| Aliases | PMS1 homolog2, mismatch repair system component |
| Species | Mouse, Mus musculus |
Pathways
Biological processes and signaling networks where the Pms2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- abnormal DNA repair
- abnormal cell physiology
- abnormal class switch recombination
- abnormal male meiosis
- abnormal mismatch repair
- abnormal seminiferous tubule morphology
- abnormal sperm flagellum morphology
- abnormal sperm head morphology
- chromosomal instability
- coiled sperm flagellum
- decreased male germ cell number
- globozoospermia
- increased B cell derived lymphoma incidence
- increased T cell derived lymphoma incidence
- increased adenocarcinoma incidence
- increased carcinoma incidence
- increased hemangioma incidence
- increased incidence of tumors by chemical induction
- increased liver adenoma incidence
- increased lymphoma incidence
- increased sarcoma incidence
- male infertility
- oligozoospermia
- premature death
- short sperm flagellum
- small testis
- teratozoospermia