Target List
Cell Surface & Cell Lineage Markers
CCR1, CD164, CD1D, CD2, CD34, CD3D, CD3G, CD4, CD44, CD80, CD86, CD8A, CSF1 (MCSF), DLL1 (DELTA1), FLT3LG, FUT10, FZD1, CHST15, IL31RA, IL6ST (GP130), JAG1, JAG2, KDR (VEGFR3), KIT (CD117), KITLG (SCF), KITLG (SCF), LRMP, MAL, NOTCH2, NOTCH4, PECAM1, PTPRC, SFXN1, STIM2, TEK (TIE-2, TIE2), TLR3, TLR4, CD27 (TNFRSF7), TNFSF11 (RANKL)
Cytokines & Growth Factors
Cytokines
CSF1 (MCSF), CSF2 (GM-CSF), FLT3LG, IL10, IL11, IL12B, IL25, IL1A, IL2, IL20, INHA, INHBA, PF4, SPP1, TNFSF11 (RANKL)
Growth Factors
CSF1 (MCSF), CSF2 (GM-CSF), IL10, IL11, IL1A, IL2, INHA, INHBA, JAG1, JAG2, KITLG (SCF), KITLG (SCF), SPP1, VEGFA
Cell Cycle Regulators
Cell Cycle Arrest
INHA, INHBA, NOTCH2
Other Regulators of the Cell Cycle
APC, HDAC4, HDAC5, HDAC7, HDAC9, IL1A, JAG2, STAT1, VEGFA
Blood Cell Activation
B-Cell Activation
HDAC4, HDAC5, HDAC7, HDAC9
T-Cell Activation
CD2, CD3D, CD3G, CD80, CD86, CD8A
Activation of Other Blood Cells
CD2, IL11, IL12B, IL2, IL31RA, PF4, TLR4
Cell Differentiation
B-Cell Differentiation
BLNK, CHST15, HDAC4, HDAC5, HDAC7, HDAC9, IL10, IL11, INHA, INHBA, CD27 (TNFRSF7)
T-Cell Differentiation
CD2, CD4, CD80, CD86, IL12B, IL2, JAG2, NOS2 (iNOS), SOCS5, CD27 (TNFRSF7)
Differentiation of Other Blood Cell Types
ANGPT1, CD3G, CSF1 (MCSF), DLL1 (DELTA1), IL11, IL20, IL31RA, INHA, INHBA, JAG1, MAL, MAP4K1 (HPK1), NCOA6, NOTCH1, NOTCH2, NOTCH4, PAX5, PF4, SPP1, TAL1, TLR3, TLR4, TNFSF11 (RANKL)
Hematopoiesis Regulators
ASH2L, CD164, CSF1 (MCSF), DLL1 (DELTA1), FUT10, IL10, IL20, IL31RA, JAG1, LMO2, MMP9, NOTCH2, NOTCH4, STIM2, TRIM10
Signal Transduction
Notch Signaling
DLL1 (DELTA1), JAG1, JAG2, NOTCH2, NOTCH4
WNT Signaling
APC, FZD1, LEF1, WNT3A
JAK / STAT Signaling
IL31RA, SOCS5, STAT1, STAT3
Cell Surface Receptors
CCR1, CD14, CD2, CD3D, CD3G, CD4, CSF2 (GM-CSF), FZD1, IL6ST (GP130), INHA, INHBA, PTPRC, CD27 (TNFRSF7)
Transcription Factors & Regulators
ASH2L, CBFB, CD80, CD86, CEBPE, CEBPG, ETS1, ETV6, GATA1, GATA2, HDAC4, HDAC5, HDAC7, HDAC9, IL31RA, LEF1, NCOA6, NOTCH1, NOTCH2, NOTCH4, PAX5, RBPJ, RUNX1 (AML1), STAT1, STAT3, TAL1, VAV1