Target List
Nuclear Receptors
Androgen Receptors & Related Molecules
AR, MED14, MED17, MED12, MED4, NR1I3, MED1, MED13, MED24, MED16
Estrogen Receptors & Related Molecules
ESR1 (ERα), ESR2 (ERβ), NCOA6, PPARGC1B (PGC-1β)
Glucocorticoid Receptors & Related Molecules
NCOA6, NR3C1 (GRL)
Retinoic Acid Receptors & Related Molecules
HMGA1, NCOA6, RARA, RARB, RARG, RXRA, RXRB, RXRG
Thyroid Hormone Receptors & Related Molecules
BRD8, MED14, MED17, MED12, MED4, NCOA3, NCOA4, NCOA6, NR1D1, NR1H3, NR1I3, NR2F6, MED1, THRA, MED13, MED24, MED16, THRB
Vitamin D Receptors & Related Molecules
MED14, MED17, MED12, MED4, MED1, MED13, MED24, MED16, VDR
Steroid Hormone Receptors
ESRRA, ESRRB, ESRRG, HNF4A, NR0B1, NR0B2, NR1D1, NR1D2 (REV-ERB), NR1H2, NR1H3, NR1H4, NR1I2, NR2C1, NR2C2 (TAK1), NR2E3, NR2F1, NR2F2, NR2F6, NR3C2, NR4A1 (NUR77), NR5A1, NR6A1, PPARA, PPARD, PPARG, RARA, RARB, RARG, RORA, RXRA, RXRB, RXRG, THRA, THRB, VDR
Other Nuclear Receptors
AHR, TRIP4
Transcription Factors & Regulators
Ligand-Dependent Nuclear Receptor Transcription Coactivators
MED14, MED17, HMGA1, MED12, MED4, NCOA6, MED1, PPARGC1A (PGC-1α), PPARGC1B (PGC-1β), MED13, MED24, MED16
Positive Regulators of Transcription
ARNT, BRD8, CREBBP (CBP), ESR2 (ERβ), KAT5, NCOA1, NCOA2, NCOA3, NCOA4, NFKB2, NR1H3, NR1I2, NR1I3, NR2C2 (TAK1), NR2F1, NR5A1, NRIP1, PSMC3, RARA, RXRA, RXRB, TRIP4
Negative Regulation of Transcription
COPS2, HDAC4, HDAC5, HDAC6, HDAC7, NCOR1, NCOR2, NR0B2, NR1D1, NR2F2, PSMC3, PSMC5, THRA, THRB
Other Transcription Factors & Regulators
AHR, AR, ESR1 (ERα), ESRRA, ESRRB, ESRRG, HDAC1, HDAC2, HDAC3, HNF4A, ITGB3BP, MTA1, NOTCH2, NR0B1, NR1D2 (REV-ERB), NR1H2, NR1H4, NR2C1, NR2E3, NR2F6, NR3C1 (GRL), NR3C2, NR4A1 (NUR77), NR6A1, KAT2B, PPARA, PPARD, PPARG, RARB, RARG, RBPJ, RORA, RXRG, VDR
Chromatin Modification Enzymes & Remodeling Factors
Histone Acetylation
KAT5, NCOA1, NCOA3, KAT2B
Histone Deacetylation
HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7
Chromatin Remodeling Factors
ESR1 (ERα)
Other Chromatin Remodeling Factors
HMGA1, NCOA6, PPARGC1B (PGC-1β)
Other Nuclear Receptor Co-Regulators
DDX5, TGS1, NONO