Arpc2

Enables several functions, including AP-1 adaptor complex binding activity; ATPase binding activity; and Arp2/3 complex binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; cellular response to platelet-derived growth factor stimulus; and positive regulation of cellular component organization. Located in several cellular components, including actin cytoskeleton; dendrite; and distal axon. Part of filamentous actin. Is active in Schaffer collateral - CA1 synapse and postsynapse. Biomarker of silicosis. Orthologous to human ARPC2 (actin related protein 2/3 complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Arpc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Arpc2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Arpc2 gene, providing context for its role in the cell.