Uggt1 Gene Summary [Rat]
Enables UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Located in endoplasmic reticulum lumen and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uggt1 |
| Official Name | UDP-glucose glycoprotein glucosyltransferase 1 [Source:RGD Symbol;Acc:619710] |
| Ensembl ID | ENSRNOG00000014901 |
| Bio databases IDs | |
| Aliases | UDP-glucose glycoprotein glucosyltransferase 1 |
| Synonyms | 0910001L17RIK, A930007H10RIK, AA589501, AI448372, C820010P03Rik, GT, HUGT1, rUGT1, UDP-glucose glycoprotein glucosyltransferase 1, UGCGL1, UGGG1, Uggt, UGT1, Ugtr |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Uggt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- thioredoxin-like domain
- catalytic domain
- non-catalytic domain
- Glucosyltransferase 24
- UDP-glucose:glycoprotein glucosyltransferase
- enzyme
- protein binding
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Golgi Apparatus
- Endoplasmic Reticulum
- ER-to-Golgi intermediate compartment
- cytosol
- endoplasmic reticulum lumen
- nuclear envelope
- smooth endoplasmatic reticulum
- rough endoplasmatic reticulum
- pre-Golgi intermediate vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Uggt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- 'de novo' posttranslational protein folding
- protein N-linked glycosylation via asparagine
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- extracellular vesicular exosome
- macromolecular complex
- endoplasmic reticulum
- endoplasmic reticulum-Golgi intermediate compartment
Molecular Function
What the gene product does at the molecular level
- protein binding
- unfolded protein binding
- UDP-glucose:glycoprotein glucosyltransferase activity