Details
| Type | Protein Coding |
| Official Symbol | TNF |
| Official Name | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] |
| Ensembl ID | ENSG00000228978 |
| Bio databases IDs | |
| Aliases | tumor necrosis factor |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the TNF gene in human plays a role, providing insight into its function and relevance in health or disease.
- 14-3-3-mediated Signaling
- Activation of IRF by Cytosolic Pattern Recognition Receptors
- Acute Phase Response Signaling
- Adipogenesis pathway
- Adrenomedullin signaling pathway
- Agranulocyte Adhesion and Diapedesis
- Airway Pathology in Chronic Obstructive Pulmonary Disease
- Allograft Rejection Signaling
- Altered T Cell and B Cell Signaling in Rheumatoid Arthritis
- Antioxidant Action of Vitamin C
- Apelin Liver Signaling Pathway
- Apoptosis Signaling
- Aryl Hydrocarbon Receptor Signaling
- Atherosclerosis Signaling
- Autophagy
- Ceramide Signaling
- Cholecystokinin/Gastrin-mediated Signaling
- Colorectal Cancer Metastasis Signaling
- Communication between Innate and Adaptive Immune Cells
- Crosstalk between Dendritic Cells and Natural Killer Cells
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- ASTHMA SUSCEPTIBILITY TO
- MALARIA SUSCEPTIBILITY TO MALARIA RESISTANCE TO INCLUDED
- MIGRAINE WITH OR WITHOUT AURA SUSCEPTIBILITY TO 1