Ssx2ip Gene Summary [Mouse]
Predicted to enable protein domain specific binding activity. Acts upstream of or within regulation of Rac protein signal transduction and regulation of cell motility. Located in cell leading edge; centriolar satellite; and ciliary basal body. Orthologous to human SSX2IP (SSX family member 2 interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ssx2ip |
| Official Name | synovial sarcoma, X 2 interacting protein [Source:MGI Symbol;Acc:MGI:2139150] |
| Ensembl ID | ENSMUSG00000036825 |
| Bio databases IDs | |
| Aliases | synovial sarcoma, X 2 interacting protein |
| Synonyms | ADIP, AU042321, hMsd1, LOC100909794, LOC308023, SSX family member 2 interacting protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ssx2ip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Afadin- and alpha -actinin-Binding
- protein domain specific binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- Huntington disease
- peripheral arterial disease
- small cell lung cancer
- androgenic alopecia
role in cell
- accumulation in
- invasion
- anchoring
- cycling
- length
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- centriolar satellite
- basal bodies
- centrosome
- intercalated disks
- anchoring junction
- microvilli
- cell membrane leading edge
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ssx2ip gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- centrosome cycle
- cilium morphogenesis
- regulation of Rac protein signal transduction
- intraflagellar transport involved in cilium morphogenesis
- regulation of cell motility
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- nucleus
- adherens junction
- cytoplasm
- cilium basal body
- cell leading edge
- centriolar satellite
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein binding