Acad10 Gene Summary [Rat]
Predicted to enable flavin adenine dinucleotide binding activity; oxidoreductase activity, acting on the CH-CH group of donors; and oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Predicted to be involved in fatty acid metabolic process. Predicted to be located in mitochondrion. Orthologous to human ACAD10 (acyl-CoA dehydrogenase family member 10). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Acad10 |
| Official Name | acyl-CoA dehydrogenase family, member 10 [Source:RGD Symbol;Acc:1310159] |
| Ensembl ID | ENSRNOG00000037815 |
| Bio databases IDs | |
| Aliases | acyl-CoA dehydrogenase family, member 10 |
| Synonyms | 2410021P16RIK, acyl-CoA dehydrogenase family member 10, acyl-CoA dehydrogenase family, member 10, acyl-Coenzyme A dehydrogenase family, member 10, MGC5601, RGD1310159 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Acad10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- epoxide hydrolase N-terminal domain-like phosphatase
- noncanonical pyrimidine nucleotidase, YjjG family
- Acyl-CoA dehydrogenase, middle domain
- enzyme
- HAD hydrolase, family IA, variant 3
- HAD hydrolase, family IA, variant 1
- acyl-CoA dehydrogenase
- Protein Kinases, catalytic domain
- Acyl-CoA dehydrogenase, C-terminal domain
- Phosphotransferase enzyme family
- Haloacid Dehalogenase-like Hydrolases
- Acyl-CoA dehydrogenase, N-terminal domain
- haloacid dehalogenase-like hydrolase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- chronic obstructive pulmonary disease
- esophageal carcinoma formation
- age-related macular degeneration
- coronary artery disease
- myocardial infarction
- gout
- esophageal carcinoma
- atrial fibrillation
- systemic lupus erythematosus
regulates
- fatty acid
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Acad10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid beta-oxidation
- fatty acid beta-oxidation using acyl-CoA dehydrogenase
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- acyl-CoA dehydrogenase activity
- flavin adenine dinucleotide binding