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GeneGlobe ID: PHS-3000Z | Cat. No.: | QIAseq Targeted DNA Pro Panels

QIAseq Targeted DNA Pro Human Comprehensive Cancer Research Panel

Kit containing ALL reagents (except indexes) for targeted DNA sequencing

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Product Specification

Target List

Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build

Brain Cancers
Anaplastic Glial Tumors​
CDKN2A (P16INK4A)CDKN2B (p15INK4b)MDM2PTENRB1TP53 (p53)
Astrocytomas​
ATRXBRAFCHEK2 (RAD53)FGFR1IDH1IDH2KRASNOTCH1PTPN11RB1TP53 (p53)
Ependymomas​
CDKN2A (P16INK4A)CDKN2B (p15INK4b)H3-3ANF2NOTCH1
Glioblastomas​
ALKAPCBCORBRAFCDK4CDK6CDKN2A (P16INK4A)CDKN2B (p15INK4b)CREBBP (CBP)EGFR (ERBB1)ERBB2 (HER-2, NEU)FGFR3H3-3AH3C2IDH1IDH2KIT (CD117)MDM2METMLH1MSH2MTORMYCNOTCH1NRASPIK3CA (p110-alpha)PMS2PTENRB1STK11 (LKB1)TERTTP53 (p53)
Gliomas​
ACVR1 (ALK2)BRCA2CHEK2 (RAD53)FGFR1H3-3APDGFRAPIK3CA (p110-alpha)PTENTP53 (p53)
High-Grade Gliomas​
ATRXBRAFCICEGFR (ERBB1)FUBP1IDH1IDH2
Medulloblastomas​
BRCA2CDK4CREBBP (CBP)CTNNB1FGFR1GLI2IDH1IDH2MSH2MYCMYCNNRASPIK3CA (p110-alpha)PTCH2SMARCA4SMARCB1SUFUTP53 (p53)
Meningiomas​
CDKN2A (P16INK4A)CDKN2B (p15INK4b)NF2PTEN
Oligodendrogliomas​
IDH1IDH2MSH2NOTCH1TERT
Breast Cancers
Carcinomas​
ATMBARD1BRCA1BRCA2BRIP1CDK12CDK4CHEK1CHEK2 (RAD53)EGFR (ERBB1)ERBB2 (HER-2, NEU)ESR1 (ERα)FANCLKIT (CD117)KRASMETMLH1MLH3MSH2MSH3MSH6PALB2PDGFRAPIK3CA (p110-alpha)PMS1PMS2RAD51BRAD51CRAD51DRAD54L
Ductal Carcinomas​
ARCCND1CDH1 (E-Cadherin)CYP2D6FANCD2FBXW7FGFR1FGFR2MRE11MYCNBNNTRK3PPM1DPPP2R1ARB1CC1SF3B1SLC22A18STK11 (LKB1)TP53 (p53)
ER-Positive Carcinomas​
CDH1 (E-Cadherin)RB1CC1SF3B1
HER-Positive Carcinomas​
ARCCND1FANCD2NTRK3PPM1DRB1CC1
Metastatic Breast Cancers​
AKT1BRCA1BRCA2ERBB2 (HER-2, NEU)ERBB3ESR1 (ERα)MDM2NF1PALB2PIK3CA (p110-alpha)PTEN
Mismatch Repair (MMR) Genes​
MLH1MSH2MSH6PMS2
Colorectal Cancers
Adenocarcinomas​
APCARID1AATMAXIN2BARD1BAXBMPR1A (ALK3)BRAFBRCA1BRCA2BRIP1BUB1BUB1BCDK12CDKN2A (P16INK4A)CHEK1CHEK2 (RAD53)CTNNB1DCCDLC1EGFR (ERBB1)EP300ERBB2 (HER-2, NEU)ERBB3ESR1 (ERα)FANCLFBXW7FGFR1FGFR3FLCNGNASHRASKIT (CD117)KRASMAP2K1MCCMETMLH1MLH3MSH2MSH3MSH6MUTYHMYCNRASPALB2PDGFRAPDGFRLPMS1PMS2POLD1POLEPTENPTPN12PTPRJRAD51BRAD51CRAD51DRAD54BRAD54LRETRNF43SMAD4 (MADH4)SOX9SRCSTK11 (LKB1)TCF7L2TGFBR2TP53 (p53)
Metastatic Colorectal Cancers​
AKT1ATMBRAFERBB2 (HER-2, NEU)KRASMETNRASPIK3CA (p110-alpha)
Mismatch Repair (MMR) Genes​
EPCAMMLH1MSH2MSH6PMS2
Other Colorectal Cancer Genes​
DPYDERCC1TYMSUGT1A1
Lung Cancers
Adenocarcinomas​
ABL1AKT1ALKATMBRAFCCND1CD274 (PD-L1)CD274 (PD-L1)CDK4CDKN2A (P16INK4A)CTNNB1DDR2EGFR (ERBB1)ERBB2 (HER-2, NEU)FGFR1FGFR3HRASKRASMAP2K1MAP3K8METMYCMYCNNRASNTRK1PIK3CA (p110-alpha)PPP2R1BPRKNPTENRETROS1SLC22A18STK11 (LKB1)TP53 (p53)TSC2
Malignant Pleural Mesotheliomas​
BAP1NF2
Non-Small Cell Lung Cancers (NSCLC)​
AKT1ALKATMBARD1BRAFBRCA1BRCA2BRIP1CCND1CDK12CDK4CDKN2A (P16INK4A)CHEK1CHEK2 (RAD53)CTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)FANCLFGFR3HRASIDH1IRF1KIT (CD117)KRASMAP2K1METMLH1MLH3MSH2MSH3MSH6MYCNRASPALB2PDGFRAPIK3CA (p110-alpha)PMS1PMS2PTENRAD51BRAD51CRAD51DRAD54LRETROS1TP53 (p53)
Small Cell Lung Cancers (SCLC)​
CD274 (PD-L1)CD274 (PD-L1)HRASMYCMYCNNTRK1PIK3CA (p110-alpha)PPP2R1BPTENRB1TP53 (p53)
Squamous Cell Carcinomas​
BRAFCD274 (PD-L1)CD274 (PD-L1)CDKN2A (P16INK4A)DDR2EGFR (ERBB1)FGFR1FGFR3HRASMAP3K8MYCMYCNNTRK1PIK3CA (p110-alpha)PPP2R1BPTENSLC22A18TP53 (p53)TSC2
Myeloid Neoplasms
Acute Lymphoblastic Leukemia (ALL)​
ABL1ABL2 (ARG)BIRC3 (c-IAP2)BRAFBTKCDKN2A (P16INK4A)CDKN2B (p15INK4b)CREBBP (CBP)CRLF2 (TSLPR)EBF1EP300ETV6FBXW7FLT3GATA3HRASIKZF1IL7RJAK1JAK2JAK3KDM6AKMT2AKRASMYCNOTCH1NRASPAX5PDGFRBPLCG2PTENPTPN11RUNX1 (AML1)SF3B1SH2B3TP53 (p53)
Acute Myeloid Leukemia (AML)​
ANKRD26ASXL1ATRXBRCA1BRCA2CBFBCBLBCBLCCCND2CDC25CCEBPACUX1DCKDDX41DHX15DNMT3AELANEETV6FLT3GATA1GATA2GNASHRASIDH1IDH2IKZF1IKZF2IKZF3JAK2KDM6AKIT (CD117)KMT2AKRASLUC7L2MTORNPM1NRASNUP214PDGFRAPICALMPRPF8PTPN11RB1RBBP6RPS14RUNX1 (AML1)SF3B1SLC29A1SMC1ATERTTET1TET2TP53 (p53)U2AF1U2AF2WT1ZEB2
Acute Promyelocytic Leukemia (APML; APL)​
CEBPANPM1NUMA1RARARUNX1 (AML1)
Atypical Chronic Myeloid Leukemia (aCML)​
ASXL1CBLCEBPAEZH2FLT3JAK2KRASNPM1NRASRUNX1 (AML1)SETBP1SRSF2TET2U2AF1
Chronic Lymphocytic Leukemia (CLL)​
ATRXBCL2BIRC3 (c-IAP2)BRAFCBLBCCND2CD38CUX1GNASGNB1LUC7L2MYD88NOTCH1NRASPTPN11SF3B1TP53 (p53)U2AF2XPO1ZAP70
Chronic Myeloid Leukemia (CML)​
ABL1ASXL1BCORBCRBRAFCBLCREBBP (CBP)DNMT3ADNMT3BEZH2IDH1IDH2IKZF1JAK2KRASNPM1NRASRUNX1 (AML1)TET1TET2TP53 (p53)WT1
Chronic Myelomonocytic Leukemia (CMML)​
ASXL1BCORBCORL1CBLCEBPADNMT3AEZH2FLT3IDH1IDH2JAK2KIT (CD117)KRASMPLNF1NPM1NRASPHF6PTPN11RUNX1 (AML1)SETBP1SF3B1SRSF2STAG2TET2TP53 (p53)U2AF1ZRSR2
Hairy Cell Leukemia​
BRAFCDKN1B (P27KIP1)MAP2K1TP53 (p53)
Juvenile Myelomonocytic Leukemia​
ARHGAP26CBLKRASNRASPTPN11
Acute Lymphocytic Lymphomas​
BIRC3 (c-IAP2)BTKCDKN2A (P16INK4A)CDKN2B (p15INK4b)MYCNOTCH1PLCG2SF3B1TP53 (p53)
B Cell Lymphomas​
BCL6BRAFCD79ACHEK2 (RAD53)EZH2MAP2K1MYD88STAT6TNFRSF14TP53 (p53)
Burkitt Lymphomas​
CBLBGNA13H1-4MTORMYC
Diffuse Large B Cell Lymphomas​
B2MBCL2CBLBGNA13H1-4KMT2DMTORPIM1PRPF8SOCS1TNFAIP3
Follicular Lymphomas​
ARID1ABCL10BCL2CARD11CREBBP (CBP)EP300EZH2FOXO1KMT2DMEF2B
Mantle Cell Lymphomas​
ATMCCND1
Marginal Zone Lymphomas​
KLF2MYD88NOTCH2TNFAIP3TP53 (p53)
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas​
BCL10TNFAIP3
Non-Hodgkin Lymphomas​
BRAFCASP10 (MCH4)NRASPIK3CA (p110-alpha)RAD54BRAD54LTP53 (p53)
Primary Cutaneous Lymphomas​
CD79BMYD88
Small Lymphocytic Lymphomas​
ATRXBCL2CBLBCCND2CUX1GNASLUC7L2U2AF2XPO1
T Cell Lymphomas​
ARID1BATMCBLBCCR4DNMT3AIDH1IDH2INO80JAK1JAK3RHOASETD2STAT3STAT5BTET2
Myelodysplastic Syndromes​
ANKRD26ASXL1ATRXBCORBCORL1CALRCBLCEBPACSF3R (GM-CSFR)CUX1DDX41DKC1DNMT3AETNK1ETV6EZH2FLT3GATA2GNASGNB1IDH1IDH2JAK2JAK3KIT (CD117)KRASMPLNF1NPM1NRASPHF6PIGAPPM1DPTPN11RAD21RUNX1 (AML1)SAMD9SAMD9LSETBP1SF3B1SMC3SRP72SRSF2STAG2STAT3TERCTERTTET2TP53 (p53)U2AF1WT1ZRSR2
Myeloproliferative Neoplasms​
ASXL1BCORCALRCBLCSF3R (GM-CSFR)DNMT3AETV6EZH2IDH1IDH2JAK2KIT (CD117)MPLNOTCH1NRASPDGFRARUNX1 (AML1)SETBP1SF3B1SH2B3SRSF2STAT3STAT5BTET2TP53 (p53)U2AF1ZRSR2
Essential Thrombocythemia​
ASXL1CBLIDH2JAK2MPLSF3B1TET2TP53 (p53)
Multiple Myeloma​
ATMBARD1BRAFBRCA1BRCA2BRIP1CHEK1CHEK2 (RAD53)CXCR4EGFR (ERBB1)ERBB2 (HER-2, NEU)FANCLFGFR3IDH1IDH2KIT (CD117)KRASMETNRASPALB2PDGFRARAD51BRAD51CRAD51DRETTP53 (p53)
Plasma Cell Myeloma​
HRASMTORRB1SLC29A1
Polycythemia Vera​
ASXL1DNMT3AEZH2IDH1JAK2NRASTET2TP53 (p53)
Primary Myelofibrosis​
ASXL1CBLDNMT3AEZH2IDH1IDH2JAK2MPLNF1NRASSETBP1SF3B1SRSF2TET2TP53 (p53)
Systemic Mastocytosis​
ASXL1CBLDNMT3AETV6EZH2IDH2JAK2KIT (CD117)KRASNPM1NRASRUNX1 (AML1)SETBP1SF3B1SRSF2TET2TPSAB1U2AF1
Waldenstrom Macroglobulinemia​
CXCR4MYD88
Ovarian Cancers
Endometrioid Carcinomas​
CDKN2A (P16INK4A)CTNNB1FANCFPOLEPPP2R1A
Epithelial Carcinomas​
ABRAXAS1ARID1AATMBARD1BRAFBRCA1BRCA2BRIP1CCNE1CDK12CHEK1CHEK2 (RAD53)ERBB2 (HER-2, NEU)ERCC1KRASMRE11NBNNF1PALB2PIK3CA (p110-alpha)PTENRAD51BRAD51CRAD51DRB1TP53 (p53)WT1
Granulosa Cell Tumors​
AKT1FOXL2
Mixed Adenosquamous Carcinomas​
AKT1ATRATRXBLMCCND1CCND2CCNE1CDH1 (E-Cadherin)DICER1ERBB3FANCAFANCCFANCD2FANCEFANCFFANCIFANCLFANCMFBXW7FGFR1FGFR2FGFR3KIT (CD117)MYCOPCML (OBCAM)PDGFRAPIK3R1 (p85-ALPHA)POLEPRKNRAD50RAD51RAD52RAD54LRB1RPA1SMARCA4STK11 (LKB1)
Mucinous Carcinomas​
ATRXCDKN2A (P16INK4A)ERBB3PDGFRA
Serous Carcinomas​
ATRATRXBLMCCND1CCND2CCNE1CDH1 (E-Cadherin)CDKN2A (P16INK4A)DICER1ERBB3FANCAFANCCFANCD2FANCEFANCFFANCGFANCIFANCLFANCMFBXW7FGFR1FGFR2FGFR3KIT (CD117)MYCPPP2R1ARAD50RAD51RAD52RAD54LRB1RPA1SMARCA4
Mismatch Repair (MMR) Genes​
MLH1MSH2MSH6PMS2
Pancreatic Cancers
Adenocarcinomas​
ATMCDKN2A (P16INK4A)CFTRFANCCFANCGMLH1MSH2MSH6PALB2PALLDPMS2PRSS1SMAD4 (MADH4)SPINK1STK11 (LKB1)TP53 (p53)
Advanced Ductal Adenocarcinomas​
BRAFBRCA1BRCA2ERBB2 (HER-2, NEU)KRASMDM2PIK3CA (p110-alpha)
Ductal Carcinomas​
APCARID1ACDK6CTNNB1ERBB3FBXW7FGFR1GNASKDM6AKRASMETMYCNRASPIK3R3POLEPREX2PTCH1PTENRNF43ROBO2SLC29A1SOX9TCF7L2
Mismatch Repair (MMR) Genes​
MLH1MSH2MSH6PMS2
Prostate Cancers
Adenocarcinomas​
ABRAXAS1APCARATRBARD1BRAFBRIP1CDK12CHEK1CHEK2 (RAD53)EPHB2ERGETV1ETV4ETV5FANCAFANCLFGFR1FOXA1GEN1HRASIDH1KDM6AKLF6KMT2DKRASMAD1L1MED12MRE11MXI1MYCNBNPIK3R1 (p85-ALPHA)PPP2R2APTENRAD51BRAD51CRAD51DRAD54LRAF1RB1SPOPTP53 (p53)ZFHX3
Advanced Prostate Cancers​
AKT1ATMBRCA1BRCA2PALB2PIK3CA (p110-alpha)PTEN
Ductal Carcinomas​
CTNNB1
Mismatch Repair (MMR) Genes​
MLH1MSH2MSH6PMS2

Product Resources

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Resources

Application Notes (1)
BeckmanCoulter QIAseq DNA Pro Panels Biomek i7
PDF (1MB)
Brochures & Guides (1)
QIAseq® Targeted DNA Pro Panels
PDF (95KB)
Eco-friendlier* products for gaining biological insights using targeted DNA sequencing
Kit Handbooks (2)
QIAseq Targeted DNA Pro Handbook for Illumina
PDF (976KB)
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Illumina NGS systems
QIAseq Targeted DNA Pro Handbook for Thermo
PDF (1MB)
For ultrasensitive targeted next-generation sequencing of DNA for Ion Torrent NGS systems
Technical Information and Important Notes (1)
A Sample to Insight NGS solution for myeloid neoplasms: Redefined amplicon sequencing for low-variant detection and interpretation
PDF (2MB)
Template Files (1)
QIAseq Targeted DNA Pro Template File
ZIP (212KB)
Safety Data Sheets (1)
Safety Data Sheets
Certificates of Analysis (1)
Certificates of Analysis
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Introducing the QIAseq Targeted DNA Pro Human Comprehensive Cancer Research Panel, a cutting-edge addition to our QIAseq Targeted DNA Pro Panels lineup, specifically designed for NGS applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq Targeted DNA Pro Human Comprehensive Cancer Research Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting NGS, or any other sophisticated analyses, this product from our QIAseq Targeted DNA Pro Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq Targeted DNA Pro Human Comprehensive Cancer Research Panel and elevate your work to new heights.
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