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GeneGlobe ID: JHS-001Z | Cat. No.: | QIAseq RNA Fusion XP Panels

QIAseq RNA Fusion XP Leukemia Panel

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

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Product Specification

Target List

Covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.Analyzes the expression of the targeted genes.Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build.

Acute Leukemia of Ambiguous Lineage
ABL1AFF1BCRCT45A2ETV6EWSR1GPHNKMT2AMLLT10MN1NUP214PBX1SETTCF3ZNF384
Acute Lymphoblastic Leukemia (ALL)
ABL1ABL2 (ARG)ACTN4AFDNAFF1AFF3AFF4AGGF1ANLNASNSATF7IPAUTS2BCL9BCRBTBD18CASC5CREBBP (CBP)CSF1RDDX3XEBF1ELLELNEML1EP300EPS15ESRRBETV6EWSR1FGFR1FGFR1OPFLT3FOXO4FOXP1FRYLGAS7GPHNHLFHNRNPUL1INPP5DJAK2KMT2AKMT2ELNP1MAML2MEF2DMLLT1MLLT10MLLT3MN1MNX1MYBMYCNCOA2NOTCH1NUP214NUP98P2RY8PAX5PBX1PCM1PDGFRBPICALMPMLPRDM16RAP1GDS1RARARCSD1RUNX1 (AML1)SALL2SETSFPQSPI1SSBP2STILSTMN1TAF15TAL1TCF3TCF7TET1USP9XZBTB16ZMIZ1ZMYM2ZNF384ZNF521ATMBRAFCDKN2A (P16INK4A)CREBBP (CBP)CSF3R (GM-CSFR)DNM2EGFR (ERBB1)FBXW7GATA2HRASMAP2K1MLH1PAX5PDGFRAPTENSMARCB1
Acute Myeloid Leukemia (AML)
ABI1ABI2ABL1AFDNAFF1AFF4ALKANLNARHGAP26ARHGEF12BCORBCRCASC5CBFA2T3CBFBCBLCCDC88CCEP170BCHD1CHIC2CREBBP (CBP)DAB2IPDDX10DEKDHHELLEP300EPS15ERGETV6FGFR1FIP1L1FLNAFNBP1FOXO3FOXO4FRYLFUSGAS7GATA1GLIS2GPHNHAUS1HOXA9HOXC11HOXC13HOXD13IRF2BP2JAK2KAT6AKDM5AKIAA1524KMT2ALASP1LNP1LPPLYNMAML2MECOMMKL1MLF1MLLT1MLLT10MLLT11MLLT3MLLT6MN1MNX1MYBMYH11MYO1FNCKIPSDNCOA2NF1NPM1NSD1NTRK3NUMA1NUP214NUP98PBX1PCM1PDGFRAPDGFRBPDS5APHF23PICALMPMLPRDM16PRRX1PSIP1PTPRRRANBP2RARARBM15RHEBL1RPL22RPN1RUNX1 (AML1)RUNX1T1SARNPSEPT2SEPT5SEPT6SEPT9SETSH3GL1SORBS2STAT5BTAF15TCF3TET1TFGTOP1TOP3ATRIP11UBA2USP42WHSC1L1WTIPZBTB16ZFYVE19ZNF384ASXL1ATMBCORBRAFCDKN2A (P16INK4A)CHEK2 (RAD53)CREBBP (CBP)CSF3R (GM-CSFR)DAXXDNM2FLT3GATA2IDH1IDH2JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MPLMYCNRASPBRM1PDGFRAPPM1DPTENPTPN11RAD21RETRUNX1 (AML1)SMARCB1SRSF2U2AF1WT1
Acute Myelomonocytic Leukemia (AMML)
FLNAHOXD13NUP98
B-Cell Acute Lymphoblastic Leukemia (B-ALL)
ABL1ACTN4AFF1AFF3AFF4ATF7IPBCRBTBD18EPS15ERGESRRBETV6EWSR1FUSGAS7JAK2KMT2AMAPRE1MLLT1NUP214P2RY8PAX5PBX1PCM1RUNX1 (AML1)SETSSBP2TCF3USP9XZNF384ZNF521
Blast Phase Chronic Myeloid Leukemia
ABL1BCRETV6JAK2
Chronic Eosinophilic Leukemia
ACSL6TNIP1
Chronic Lymphocytic Leukemia (CLL)
MYCNOTCH1BRAFCHEK2 (RAD53)CSF3R (GM-CSFR)MAP2K1TERT
Chronic Myeloid Leukemia (CML)
ABL1BCRCCDC88CETV6JAK2MECOMMN1NDE1NUP98PCM1PDGFRBRUNX1 (AML1)ABL1CDKN2A (P16INK4A)CREBBP (CBP)CSF3R (GM-CSFR)FBXW7GATA2
Chronic Myelomonocytic Leukemia (CMML)
CREBBP (CBP)ELLETV6KMT2AMN1CSF3R (GM-CSFR)HRASSRSF2
Myelodysplastic Syndromes (MDS)
ABL1ACTN4ALKCASC5CREBBP (CBP)DEKERGETV6FRYLFUSHOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1NDE1NPM1NUP214NUP98PCM1PDGFRBPRDM16PTPRRRANBP2RUNX1 (AML1)RUNX1T1TOP1CDKN2A (P16INK4A)CSF3R (GM-CSFR)ETNK1GNASHRASRAD21SETBP1SRSF2U2AF1XPO1ZRSR2
Myeloproliferative Neoplasms
ABL1ACSL6BCRETV6FGFR1FGFR1OPFIP1L1FLT3HOXA9HOXD13JAK2LYNMECOMMLF1MN1NPM1NUP98PDGFRBPRKG2PSIP1RARARUNX1 (AML1)TNIP1ZMYM2ABL1ASXL1JAK2JAK3KRASMPLNRASSETBP1SF3B1SH2B3SRSF2
T-Cell Acute Lymphoblastic Leukemia (T-ALL)
ABL1AFDNAGGF1ASNSBCRCASC5DDX3XETV6JAK2KMT2AKMT2EMLLT1MLLT10NOTCH1NUP214PBX1RUNX1 (AML1)SALL2SETSPI1STILSTMN1TAL1TCF3TCF7
Other Leukemias
IKZF3IRF2BP2MYCNPM1PDCD1LG2SETD2
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFR (ERBB1)EML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
General Leukemia Markers
ANPEPCD19CD200CD33CD34CD38CR2FOXM1FOXO3HOXA9ITGA6KIT (CD117)MS4A1RUNX1 (AML1)
Leukemia Subtype Marker
Acute Lymphoblastic Leukemia (ALL)​
ANPEPBTG1CASP8AP2CD19CD1ACD2CD22CD33CD5CD7CD79ACD8ACR2ETV6HLA-DRAHLA-DRB1IL2RA (CD25)JUNKIT (CD117)LMO1LMO2LYL1MEIS1MMEMS4A1MYCPBX1PTPRCRB1VEGFAWT1
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
BTG1CD300ACD72CD79ACD79BCD86CDKN2A (P16INK4A)CDKN2B (p15INK4b)CRLF2 (TSLPR)EBF1ETV6HOXA9IKZF1PAX5RB1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BTKCD27 (TNFRSF7)CD4KCNN4LMO1LMO2LYL1MMP9RUNX1 (AML1)SERPINI1TAL1THBS1 (TSP-1)TLX1TLX3VPREB3
Acute Myeloid Leukemia (AML)​
ADGRE5 (CD97)ASS1BAALCBCL11BBIRC5CD200CD300ACD44CD86CD96CD99CLEC12AERGFCGR2AFLT3HAVCR2IL2RA (CD25)JUNKIT (CD117)KLF4LEF1MECOMMEIS1MMP9NPM1PTPRCTHBS1 (TSP-1)VEGFAWT1
Chronic Lymphocytic Leukemia (CLL)​
ABCA6AIM2AKT1BAXBCL2BIRC2 (c-IAP1)BTKCD19CD200CD24CD27 (TNFRSF7)CD5CD79BCXCR4IL7ITGA4 (CD49D)ITGAMJUNKCNN4LAIR1LEF1MCL1MMP9MS4A1ROR1SERPINI1SOX11THBS1 (TSP-1)TNFTTNVEGFAVPREB3WNT3
Chronic Myeloid Leukemia (CML)​
AURKAAURKBIL2RA (CD25)JUNKIT (CD117)PTCH1PTPRC
Other Leukemia Subtypes​
CD72IL2RA (CD25)SPI1
Leukemia Stem Cell & Proliferation Markers
ADGRG1BAALCBMI1CD33CD34CD44CD47CD96CD99CLEC12ACXCL12 (SDF1)CXCR4ERGFCGR2AHAVCR2IL2RA (CD25)IL3RAKIT (CD117)KLF4LAIR1LIN28AMYCPOU5F1 (OCT4)PTPRCSOX2THY1WT1
Possible Prognostic Significance
Indicator of Clinical Outcome in Leukemia​
AURKBBAALCBIRC5ERGFOXO3GATA2MECOMMEIS1RUNX1 (AML1)SPI1WT1
Acute Lymphoblastic Leukemia (ALL)​
ABCB1 (MDR1, PGY1)AKT1ANPEPBIRC5CD33CD3DCD44FLT3HOXA9IKZF1JUNMMEMYCPAX5SMYD2
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
ANPEPCD33CRLF2 (TSLPR)JUNMS4A1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BCL11BBMI1LMO1LMO2LYL1MYCTAL1TLX1TLX3
Acute Myeloid Leukemia (AML)​
ABCB1 (MDR1, PGY1)ANGPT2BAALCBCL2BIRC2 (c-IAP1)BIRC5BMI1CCNA1CD200CD34CD4CD44CD47CD96CLEC12ACXCL12 (SDF1)CXCR4ERGGATA2HAVCR2HGFIL2RA (CD25)IL3RAKLF4LEF1MECOMMEIS1MN1MYCRUNX1 (AML1)SOX11SOX2SPI1WT1XIAP
Chronic Lymphocytic Leukemia (CLL)​
ABCA6ANGPT2BCL2CD24CD38CD69ITGA4 (CD49D)KCNN4LAIR1LPLMS4A1MYCNOTCH1ROR1SOX11TTNUGT2B17VPREB3WNT3ZAP70
Chronic Myeloid Leukemia (CML)​
AURKAAURKBLIN28AMCL1PTCH1
Chemotherapy Resistance Related​
AKT1AURKBBAALCBCL2BIRC2 (c-IAP1)CD274 (PD-L1)CD274 (PD-L1)CD44CD47ERGHLA-DRAHLA-DRB1IL3RAMCL1MYCXIAP
Hypoxia & Oxidative Stress Related​
ANGPT2VEGFA
Treatment Target or Treatment Indicator​
ASS1BMI1CASP8AP2CD33CD47CD69CD96CDC25ACDKN2A (P16INK4A)CDKN2B (p15INK4b)CLEC12ACXCR4FLT3FOXM1FOXO3HAVCR2IL3RAITGAMKLF4LMO2MS4A1MYCPTCH1SERPINI1SMARCA4TAL1ZAP70
Associated with Invasiveness or Infiltration into Central Nervous System​
CXCL12 (SDF1)CXCR4ZAP70
Minimal Residual Disease​
ADGRE5 (CD97)BAALCBCL2CD19CD200CD24CD300ACD44CD47CD69CD72CD79BCD86CD99CLEC12AHAVCR2IL2RA (CD25)IL3RAITGA6NPM1PBX1WT1
Mechanistic Role in Pathogenesis
BCL11BBCL2BMI1ERGFOXM1GATA2HOXA9LMO2LPLMEIS1NOTCH1PAX5SPI1TAL1TLX1TLX3TNFVEGFAWT1
Expression Altered due to Genetic Alterations
Acute Lymphoblastic Leukemia (ALL)​
AHI1BCL11ABCL2BCL9BRD4CCND2CEBPACEBPBCEBPDCEBPECEBPGCRLF2 (TSLPR)EPORETV6HOXA1ID4IGF2BP1IL3IRS4LCKLHX4LMO1LMO2LYL1MYBMYCNKX2-5NOTCH1OLIG2TAL2TLX1TLX3
Acute Myeloid Leukemia (AML)​
MECOMNKX2-5RANBP17TCL1ATLX3
Other Leukemia Subtypes & Other Genetic Alterations​
BAALCBCL11BCRLF2 (TSLPR)ERGKIT (CD117)LMO1LPLNPM1TAL1ZAP70
Chronic Neutrophilic Leukemia (CNL)
CSF3R (GM-CSFR)
Multiple Myeloma
ATMBRAFCDKN2A (P16INK4A)EGFR (ERBB1)FBXW7HRASMYCPTENSMARCB1
Myelofibrosis
CHEK2 (RAD53)IDH1IDH2SRSF2
Myeloid Malignancies
CBLCBLBDNMT3AEZH2
Other Myeloid Neoplasms
BRAFCDKN2A (P16INK4A)CUX1FBXW7HRASMYD88PTENSTAT3

Product Resources

Detailed Target List for each Analyte
File Size: 31.27 KBLanguage: English

Resources

Safety Data Sheets (1)
Safety Data Sheets
Kit Handbooks (1)
QIAseq RNA Fusion XP Panel Handbook
PDF (3MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis
Introducing the QIAseq RNA Fusion XP Leukemia Panel, a cutting-edge addition to our QIAseq RNA Fusion XP Panels lineup, specifically designed for {{application}} applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq RNA Fusion XP Leukemia Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting {{application}}, or any other sophisticated analyses, this product from our QIAseq RNA Fusion XP Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq RNA Fusion XP Leukemia Panel and elevate your work to new heights.
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