Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Adenocarcinomas
ABL1ALKATMBRAFCDK4CDKN2A (P16INK4A)CTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)KRASMAP2K1METNRASNTRK1PIK3CA (p110-alpha)PTENRETROS1TP53 (p53)TSC2
Malignant Pleural Mesotheliomas
NF2
Non-Small Cell Lung Cancers (NSCLC)
ALKATMBARD1BRAFBRCA1BRCA2BRIP1CDK12CDK4CDKN2A (P16INK4A)CHEK1CHEK2 (RAD53)CTNNB1EGFR (ERBB1)ERBB2 (HER-2, NEU)FANCLKIT (CD117)KRASMAP2K1METMLH1MLH3MSH2MSH3MSH6NRASPALB2PDGFRAPIK3CA (p110-alpha)PMS1PMS2PTENRAD51BRAD51CRAD51DRAD54LRETROS1TP53 (p53)
Small Cell Lung Cancers (SCLC)
NTRK1PIK3CA (p110-alpha)PTENRB1TP53 (p53)
Squamous Cell Carcinomas
BRAFCDKN2A (P16INK4A)EGFR (ERBB1)NTRK1PIK3CA (p110-alpha)PTENTP53 (p53)TSC2