QuantiNova LNA PCR Focus Panel Human Epithelial to Mesenchymal Transition (EMT) | GeneGlobe

Product Specification

Target List

Up-Regulated During Epithelial-to-Mesenchymal Transition

Down-Regulated During Epithelial-to-Mesenchymal Transition

CAV2CDH1 (E-Cadherin)DSPFGFBP1IL1RNKRT19MST1R (RON)NUDT13OCLNDESI1RGS2SPP1TFPI2TSPAN13

Cell Morphogenesis

CTNNB1FOXC2JAG1RAC1SMAD2 (MADH2)SNAI1 (SNAIL)SOX10TGFB1TGFB2TGFB3TWIST1WNT11WNT5A

Cell Growth & Proliferation

AKT1BMP1BMP7CAV2CTNNB1EGFR (ERBB1)ERBB3FGFBP1FOXC2IGFBP4ILKJAG1MST1R (RON)NODALPDGFRBTGFB1TGFB2TGFB3TIMP1VCANZEB1

Cell Migration & Motility

CALD1CAV2EGFR (ERBB1)FN1ITGB1JAG1MSNMST1R (RON)NODALPDGFRBRAC1STAT3TGFB1VIM

Cytoskeleton Regulators

CAV2KRT7MAP1BPLEK2RAC1VIM

Extracellular Matrix (ECM) & Cell Adhesion Molecules

BMP1BMP7CDH1 (E-Cadherin)CDH2 (N-Cadherin)COL1A2COL3A1COL5A2CTNNB1DSC2EGFR (ERBB1)ERBB3F11RFN1FOXC2ILKITGA5ITGAVITGB1MMP2MMP3MMP9PTK2 (FAK)RAC1SERPINE1 (PAI-1)SPP1TGFB1TGFB2TIMP1VCAN

Signal Transduction

Estrogen Receptor Signaling

CAV2ESR1 (ERα)KRT19TGFB3

G-Protein Coupled Receptor Signaling

AKT1FZD7GNG11RAC1RGS2

Integrin-Mediated Signaling

COL3A1ILKITGA5ITGAVITGB1PTK2 (FAK)

Notch Signaling

FOXC2JAG1NOTCH1

Receptor Tyrosine Kinase Signaling

EGFR (ERBB1)ERBB3PDGFRBRGS2SPARC

TGFβ / BMP Signaling

BMP1BMP2BMP7COL3A1SMAD2 (MADH2)TGFB1TGFB2TGFB3

WNT Signaling

CTNNB1FZD7GSK3BWNT11WNT5AWNT5B

Transcription Factors

CTNNB1ESR1 (ERα)FOXC2GSCNOTCH1GEMIN2SMAD2 (MADH2)SNAI2SNAI3SOX10STAT3TCF3TCF4TWIST1ZEB1ZEB2

Product Resources

Array Layout for PCR Plates

File Size: 153.52 KBLanguage: English

Array Layout for Rotor-Gene Q

File Size: 153.65 KBLanguage: English

Resources

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