Target List
Eosinophilia
CR2, JAK1
Lymphoproliferative Disorders
PLAA, SH2D1A, XIAP
Mastocytosis
DNMT3A, IDH2, KIT (CD117), NRAS, RUNX1 (AML1)
Multiple Myeloma
ATM, CCND1, IDH1, IDH2, KIT (CD117), LIG4, NRAS, TP53 (p53)
Myelodysplastic Syndromes
CEBPA, DNMT3A, GATA2, GNB1, IDH1, IDH2, KIT (CD117), MPL, MSH6, NF1, NRAS, RUNX1 (AML1), SMAD9, TERC, TERT, TP53 (p53)
Myelofibrosis
DNMT3A, IDH1, IDH2, MPL, NF1, NRAS, TP53 (p53)
Myeloproliferative Neoplasms
DNMT3A, IDH1, IDH2, MPL, RUNX1 (AML1), SH2B3, TP53 (p53)
Polycythemia Vera
DNMT3A, IDH1, NRAS, TP53 (p53)
Thrombocythemia
IDH2, MPL, SH2B3, THPO, TP53 (p53)
Other Hematological Malignancies Genes
BLM, EPCAM, HRAS, MLH1, MSH2, NBN, PMS2