Target List
T-Cell Regulators
BTLA, CBLB, CD27 (TNFRSF7), CD28, FAS, FOXP3, IL15, IL2, IL2RA (CD25), IL4, LAT, TGFB1, TNFRSF14, TNFSF14
B-Cell Regulators
BTLA, CD27 (TNFRSF7), CD40 (TNFRSF5), CD40LG, FOXP1, FOXP3, HDAC9, IL4
Cytokines, Receptors & Related Proteins
CCL3L3, CCR4, CD40LG, CD70, CSF1 (MCSF), CSF2 (GM-CSF), FASLG (TNFSF6), IFNG, IL10, IL10RA, IL13, IL15, IL17A, IL1A, IL2, IL2RA (CD25), IL2RB, IL31, IL4, IL5, IL6, IL7R, LEP (Leptin), LTA (TNFB), PRF1, PTGER2, PTGS2 (COX2), TGFB1, TNFSF10 (TRAIL), TNFSF14, TNFSF8
TNF Superfamily Members & Their Receptors
CD40LG, CD70, FAS, FASLG (TNFSF6), LTA (TNFB), TNFRSF10A (TRAIL-R), TNFRSF18, TNFRSF4 (OX40), TNFRSF8, TNFRSF9, TNFSF10 (TRAIL), TNFSF14, TNFSF8
Transcriptional Regulation
CDK2, CDK4, EGR2, EGR3, EOMES, FOS, FOXP1, FOXP2, FOXP3, GATA3, HDAC9, IFNG, ING4, IRF4, JAK3, JUN, MEF2A, NFATC1, NFATC2, NFATC3, NFKB1, NHLH2, NOTCH1, STAT3, STAT6, TBX21, TGFB1
Other T-Cell Anergy Genes
CMA1, CTLA4, DGKA, DGKZ, GZMB, ICAM1, ICOS, ITCH, ITGA1, JAK1, LGALS3, PDCD1 (PD1), PDCD1 (PD1), PRKCG, RNF128, SELL (LECAM-1)