Target List
Receptors, Transporters & Channels
ABCC8, ADRB3, AQP2, CCR2, CD28, CEACAM1, CTLA4, GCGR, GLP1R, ICAM1, IL4R (CD124), INSR, NSF, RAB4A, SELL (LECAM-1), SLC2A4 (GLUT4), SNAP23, SNAP25, STX4, STXBP1, STXBP2, TNFRSF1A (TNFR1), VAMP3, VAPA
Nuclear Receptors
PPARA, PPARG
Metabolic Enzymes
ACE, ACLY, ENPP1, FBP1, G6PC, G6PD, GCK, GPD1, GSK3B, HMOX1, IDE, ME1, NOS3 (eNOS), PARP1 (ADPRT1), PRKAA1 (AMPK), PRKAG2, PRKCB, PYGL
Cytokines & Growth Factors
AGT, CCL5 (RANTES), GCG, IFNG, IL6, IL10, IL12B, INS, RETN, TGFB1, TNF, VEGFA
Signal Transduction
AKT2, DUSP4, IGFBP5, IKBKB (IKKβ), INPPL1 (SHIP2), IRS1, IRS2, MAPK8 (JNK1), MAPK14 (p38ALPHA), PIK3C2B, PIK3CD, PIK3R1 (p85-ALPHA), PTPN1 (PTP1B), TRIB3 (SKIP3)
Transcription Factors
CEBPA, FOXC2, FOXG1, FOXP3, HNF4A, PDX1, NEUROD1, NFKB1, NRF1, PPARGC1A (PGC-1α), PPARGC1B (PGC-1β), SREBF1, HNF1B, NKX2-1