Target List
Cytokines & Chemokines
CCL11 (Eotaxin), CCL2 (MCP-1), CCL22 (MDC), CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), CXCL1 (GRO1, GROa, SCYB1), CXCL10 (INP10), CXCL2 (GRO2, GROb, SCYB2), CXCL9 (MIG), FASLG (TNFSF6), IFNB1, IFNG, IL12B, IL15, IL1A, IL1B, IL1RN, IL2, IL4, IL6, CXCL8 (IL8), LTA (TNFB), LTB, TNF, TNFSF10 (TRAIL)
Inflammation
Acute Inflammation
C3, CCL5 (RANTES), CFB, F3, F8, IL1A, IL1B, IL6, INS, STAT3, STAT5B
Other Pro-Inflammatory Genes
AGT, AKT1, CCL11 (Eotaxin), CCL2 (MCP-1), CCL22 (MDC), CCR5, CD40 (TNFRSF5), CXCL1 (GRO1, GROa, SCYB1), CXCL10 (INP10), CXCL2 (GRO2, GROb, SCYB2), CXCL9 (MIG), IL15, IL1RN, IL2, IL2RA (CD25), CXCL8 (IL8), MYD88, PTGS2 (COX2), SELE, SELP, TNF, TNFRSF1B
Apoptosis
AGT, BIRC2 (c-IAP1), EGFR (ERBB1), FASLG (TNFSF6), GADD45B, IFNB1, IFNG, IL12B, IL2RA (CD25), IL4, INS, LTA (TNFB), MAP2K6 (MEK6, MKK6), MMP9, NQO1, NR4A2 (NURR1), PTGS2 (COX2), STAT1, TNFRSF1B, TNFSF10 (TRAIL), TP53 (p53), TRAF2
Anti-Apoptotic
ADM, AKT1, BCL2A1 (BFL1), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC3 (c-IAP2), CCL2 (MCP-1), CDKN1A (p21CIP1, WAF1), CSF2 (GM-CSF), F3, FAS, IL1A, IL1B, IL2, IL6, MYD88, NFKBIA (IκBα, MAD3), SOD2, STAT5B, TNF, XIAP
Immune Response
Innate Immunity
C3, CCL2 (MCP-1), CFB, IFNB1, IL12B, IL6, INS, MYD88, NFKBIA (IκBα, MAD3), STAT5B, TNF
Adaptive Immunity
C3, CCL2 (MCP-1), CD40 (TNFRSF5), CD80, ICAM1, IFNG, IL12B, IL1B, IL2, IL4, TRAF2
Other Immune Response Genes
CD83, FAS, FASLG (TNFSF6), IL1R2, CXCL8 (IL8), LTA (TNFB), LTB, TNFSF10 (TRAIL)
Type I Interferon Responsive Genes
ADM, CCL2 (MCP-1), CCL5 (RANTES), CD69, CD80, CDKN1A (p21CIP1, WAF1), CFB, CXCL10 (INP10), CXCL9 (MIG), IL15, IL1RN, IRF1, MYD88, NCOA3, STAT1, TNFSF10 (TRAIL)
Differentiation & Development
Lymphoid Differentiation & Development
CD80, CD83, IL12B, IL15, IL2, IL2RA (CD25), IL4, IRF1, STAT5B, TP53 (p53), VCAM1
Myeloid Differentiation & Development
CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF2RB, CSF3 (GCSF), IL4, MMP9, NFKBIA (IκBα, MAD3), STAT5B, TNF
Nervous System Differentiation & Development
AGT, ALDH3A2, CXCL1 (GRO1, GROa, SCYB1), EGFR (ERBB1), EGR2, IFNG, NR4A2 (NURR1), SNAP25, SOD2, STAT3, TP53 (p53)
Stress Responses
ADM, AKT1, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC2 (c-IAP1), CCND1, CDKN1A (p21CIP1, WAF1), GADD45B, IFNG, IL1A, IL1B, MAP2K6 (MEK6, MKK6), NQO1, PDGFB, PLAU (UPA), SOD2, TNF, TP53 (p53), XIAP
NFκB Signaling
Transcription Factors
NFKB1, NFKB2, NFKBIA (IκBα, MAD3), RELB, STAT1
Regulation of NFκB Signaling
BIRC2 (c-IAP1), CD40 (TNFRSF5), FASLG (TNFSF6), IL1B, MYD88, REL, RELA, TNF, TNFSF10 (TRAIL)
Transcription Factors
NFκB Signaling
NFKB1, NFKB2, REL, RELA, RELB
Other Transcription Factors
EGR2, IRF1, MYC, NR4A2 (NURR1), STAT1, STAT3, STAT5B, TP53 (p53)