Target List
Telomere Maintenance
ACD, BLM, DCLRE1C, DKC1, ERCC1, ERCC4, HSPA1L, MRE11, MYC, NBN, PARP1 (ADPRT1), PIF1, POT1, PRKDC, PTGES3, RAD50, RFC1, RTEL1, SMG6, TEP1, TERF1, TERF2, TERF2IP, TERT, TINF2, TNKS (TIN1), TNKS2, XRCC5, XRCC6
Telomere-Associated Complexes
Shelterin Complex
ACD, POT1, RAP1A, TERF1, TERF2, TINF2
Telomerase Complex
DKC1, GAR1, NHP2, NOP10, TERT, WRAP53
SLX4 (BTBD12) Complex
SLX4, ERCC1, ERCC4, EME1, MSH2, MSH3, MUS81, PLK1, TERF2, TERF2IP
Telomere Regulation
Regulation of Telomere Length
RTEL1, TEP1, TERF1, TERF2IP, TNKS (TIN1)
Shelterin Complex Regulation
DCLRE1B, KRIT1, RASSF1, RAPGEF1, TPP1
Telomerase Regulation
ABL1, AKT1, ATP5F1C, BCL2, EGF, IGF1, KRAS, MEN1, MYC, PAX8, PINX1, PPARG, PPP2R1A, PPP2R1B, PRKCA, PRKCB, RB1, SART1, SMAD3 (MADH3), SP1, SSB, TGFB1, TP53 (p53)
Other Telomere-Associated Genes
ATM, CDK2, CHEK1, CHEK2 (RAD53), HAT1, HNRNPA2B1, HNRNPD, HSP90AA1, NCL, STN1, PURA, RAD17, RIF1, SIRT2, SIRT6, TP53BP1, SUN1