Target List
Apoptosis
Pro-Apoptotic
Apaf1, Atp6v1g2, Bax, Bcl2l11, Birc2 (c-IAP2), Casp1 (Ice), Casp3, Casp7, Casp9, Cd40, Cd40lg, Cflar (Casper), Cyld, Dffa, Fas, Faslg, Gadd45a, LOC100909750 (Abl1), LOC103689977 (Casp6), LOC103694380 (Tnf), Nol3, Spata2, Sycp2, Tnfrsf10b (QuantiNova Symbol: AABR07018323.1), Tnfrsf1a (Tnfr1), Tp53 (p53)
Anti-Apoptotic
Akt1, Api5, Bcl2, Bcl2a1 (Bfl-1, A1), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Birc3 (c-IAP1), Casp2, Igf1r, Tnfrsf11b (Opg), Traf2, Xiap
Autophagy
Akt1, App, Atg12, Atg16l1, Atg3, Atg5, Atg7, Bax, Bcl2, Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Becn1, Casp3, Ctsb, Ctss, Esr1 (Erα), Fas, Gaa, Htt, Ifng, Igf1, Ins2, Irgm, LOC103694380 (Tnf), Map1lc3a, Mapk8 (Jnk1), Nfkb1, Pik3c3 (Vps34), Pten, Rps6kb1, Snca, Sqstm1, Tp53 (p53), Ulk1
Necrosis
Atp6v1g2, Bmf, Commd4, Cybb, Cyld, Defb1, Dennd4a, Dpysl4, Foxi1, Galnt5, Grb2, Hspbap1, Kcnip1, Maco1, Mag, Olr1583, Parp1 (Adprt1), Parp2, Pvr, Rab25, RGD1311517, Spata2, Sycp2, Tnfrsf1a (Tnfr1), Tnfrsf4 (Ox40), Tnfrsf8, Txnl4b