Target List
Adenoma
Tubular Adenoma
BRAF, FBXW7, KRAS
Tubulovillous Adenoma
BRAF, CTNNB1, KRAS, NRAS, PIK3CA (p110-alpha)
Villous Adenoma
BRAF, KRAS
Other Adenoma-Related Genes
APC, DMD, SMAD4 (MADH4), STK11 (LKB1), TCF7L2
Carcinoid-Endocrine Tumor
APC, CTNNB1, TP53 (p53)
Carcinoma
Adenocarcinoma
ACVR1B, AKT1, APC, ATM, ATP6V0D2, AXIN2, BAX, BLM, BMPR1A (ALK3), BRAF, BRCA1, BRCA2, BUB1B, CASP8 (FLICE), CDC27, CDH1 (E-Cadherin), CDK4, CDKN2A (P16INK4A), CHEK2 (RAD53), CTNNA1, CTNNB1, DCC, DMD, EGFR (ERBB1), ENG (EVI-1), EP300, EPCAM, ERBB2 (HER-2, NEU), FBXW7, FGFR3, FLCN, FZD3, GALNT12, GPC6, GREM1, KIT (CD117), KRAS, MAP2K4 (MKK4, JNKK1), MAP7, MET, MIER3, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, MYO1B, NRAS, PALB2, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PMS1, PMS2, POLD1, POLE, PTEN, PTPN12, RET, RPS20, SLC9A9, SMAD2 (MADH2), SMAD4 (MADH4), SRC, STK11 (LKB1), TCERG1, TCF7L2, TGFBR2, TP53 (p53), WBSCR17
Neuroendocrine
BRAF, KRAS
Serrated Carcinoma
BRAF, PIK3CA (p110-alpha)
Squamous Cell Carcinoma
KRAS, TP53 (p53)
Other Carcinomas
BRCA2, CDKN2A (P16INK4A)
Aberrant Crypt Foci
Hyperplastic Aberrant Crypt Foci
BRAF, KRAS
Other Aberrant Crypt Foci
APC
Serrated Polyp
Admixed Hyperplastic Polyp-Adenoma
BRAF, KRAS
Hyperplastic Polyp
BRAF, CTNNB1, KRAS
Serrated Adenoma
APC, BRAF, KRAS, WBSCR17
Serrated Fibroblastic Polyp-Intramucosal Perineurioma
BRAF
Other Tumors
Borderline
KRAS
Hamartoma
CTNNB1
Juvenile Polyp
APC
Neoplasm
APC, KRAS
Peutz-Jeghers Polyp
APC
Other Colorectal Cancer Genes
CTNNA1, MLH3, PALB2, PMS2, SCG5, SRC