Target List
Carcinoid-Endocrine Tumor
Atypical
KRAS, PIK3CA (p110-alpha), TP53 (p53)
Typical
PIK3CA (p110-alpha)
Carcinoma
Non-Small Cell Lung Cancer
ALK, AMER1, APC, ATM, ADGRB3, BRAF, CDKN2A (P16INK4A), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), FGFR3, GRM8, HRAS, JAK2, KRAS, MET, MUC16, NF1, NFE2L2, NRAS, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PKHD1, PTEN, RB1, RET, SMARCA4, STK11 (LKB1), TNFAIP3, TP53 (p53)
Small Cell Lung Cancer
ALK, AMER1, ARID1A, ATM, ADGRB3, CDKN2A (P16INK4A), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB4, FBXO7, FBXW7, FGFR1, FHIT, GRM8, HRAS, KDR (VEGFR3), KIT (CD117), KRAS, LRP1B, MET, KMT2D, MUC16, MYC, NF1, NOTCH1, NTRK1, NTRK2, NTRK3, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PKHD1, PTEN, PTPRD, RARB, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMARCA4, TNFAIP3, TP53 (p53)
Squamous Cell Carcinoma
AKT1, ALK, AMER1, APC, ARID1A, ATM, ADGRB3, BRAF, CDKN2A (P16INK4A), CDKN2B (p15INK4b), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB2 (HER-2, NEU), ERBB4, FBXO7, FBXW7, FGFR1, FGFR2, FGFR3, FHIT, GRM8, HRAS, JAK2, KDR (VEGFR3), KEAP1, KIT (CD117), KRAS, LRP1B, MAP2K1, MDM2, MET, MGA, MLH1, KMT2D, MUC16, MYC, NF1, NFE2L2, NOTCH1, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PKHD1, PTEN, PTPRD, RARB, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMAD4 (MADH4), SMARCA4, STK11 (LKB1), TNFAIP3, TP53 (p53), TSC1, U2AF1
Acinar Adenocarcinoma
BRAF, EGFR (ERBB1), KRAS
Adenocarcinoma
AKT1, ALK, AMER1, APC, ARID1A, ATM, ADGRB3, BAP1, BRAF, CDKN2A (P16INK4A), CDKN2B (p15INK4b), CREBBP (CBP), CTNNB1, DDR2, EGFR (ERBB1), EPHA5, ERBB2 (HER-2, NEU), ERBB4, FBXO7, FBXW7, FGFR1, FGFR2, FGFR3, FHIT, GRM8, HRAS, JAK2, KDR (VEGFR3), KEAP1, KIT (CD117), KRAS, LRP1B, MAP2K1, MDM2, MET, MGA, MLH1, KMT2D, MUC16, MYC, NF1, NFE2L2, NOTCH1, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA (p110-alpha), PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PKHD1, PTEN, PTPRD, RARB, RASSF1, RB1, RBM10, RET, RIT1, ROS1, RUNX1T1, SETD2, SMAD4 (MADH4), SMARCA4, SOX2, STK11 (LKB1), TNFAIP3, TP53 (p53), TSC1, U2AF1
Blastoma
CTNNB1, TP53 (p53)
Bronchioalveolar Adenocarcinoma
CDKN2A (P16INK4A), EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, NF1, STK11 (LKB1), TP53 (p53)
Carcinosarcoma
EGFR (ERBB1)
Giant Cell
EGFR (ERBB1)
Large Cell
BRAF, DDR2, CDKN2A (P16INK4A), EGFR (ERBB1), EPHA5, FGFR1, FGFR3, HRAS, KEAP1, KRAS, NRAS, NTRK1, NTRK3, PIK3CA (p110-alpha), STK11 (LKB1), TP53 (p53)
Lymphoepithelioma-Like
EGFR (ERBB1), TP53 (p53)
Micropapillary Adenocarcinoma
BRAF, EGFR (ERBB1), KRAS
Mixed Adenosquamous
EGFR (ERBB1), KRAS, PIK3CA (p110-alpha), STK11 (LKB1), TP53 (p53)
Mixed Small Cell Carcinoma-Adenocarcinoma
CREBBP (CBP), DDR2, EGFR (ERBB1), TP53 (p53)
Mucoepidermoid Carcinoma
EGFR (ERBB1)
Oncocytic Adenocarcinoma
EGFR (ERBB1), KRAS
Pleomorphic Carcinoma
EGFR (ERBB1), KIT (CD117), KRAS, TP53 (p53)
Sarcomatoid Carcinoma
EGFR (ERBB1), KRAS
Terminal Respiratory Unit Type Adenocarcinoma
EGFR (ERBB1)
Undifferentiated Carcinoma
EGFR (ERBB1), KRAS, MUC16, PKHD1, TP53 (p53)
Other Carcinomas
ARID1A, CTNNB1, HRAS, NRAS
Other Cancer Subtypes
Hyperplasia
EGFR (ERBB1), KRAS
Mucinous Proliferation
KRAS
Neoplasm
EGFR (ERBB1), KRAS