Target List
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
COL14A1, COL1A2, COL4A3, COL5A1, COL5A3, DCN, VTN
Extracellular Matrix (ECM) Remodeling Enzymes
CTSK, F3, FGA, TIMP1, PLAUR (uPAR), MMP1, MMP2, MMP3, MMP9, PLAT (TPA), PLAU (UPA), PLG, SERPINE1 (PAI-1)
Cell Adhesion Molecules
ITGA1, ITGA4, ITGA5, ITGA6, ITGAV, ITGB1, ITGB5, ITGB6, ITGA2, TNC
Cytoskeleton Regulators
ACTC1, RHOG, RHOC, LOC100009332
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1), CCL4 (MIP-1B), IFNG, IL10, IL1A, IL1B, IL2, IL4, IL6, CXCL8, LOC100354804 (CXCL2), CD40LG
Growth Factors
CSF2, CTGF, FGF2 (BFGF), HGF, IGF1, EGF, HBEGF (DTR), MIF, FGF10, PDGFA, INHBA, CSF3 (GCSF), PDGFB, LIF, TGFB1, TNF, VEGFA
Signal Transduction
TGFβ / BMP Signaling
TGFBR3, INHBA, TGFB1, TGFB3, STAT3
WNT Signaling
CTNNB1, DKK3, WISP3, WNT2, WNT5A
Kinases
PIK3CA (p110-alpha), MAPK1 (ERK2), PTK2, MAPK3 (ERK1), PTEN
Cell Surface Receptors
IL6ST (GP130), EGFR (ERBB1), TGFBR3, TLR4
Other Signal Transduction Genes
PTGS1 (COX1), PLOD2, GRB2, PTGS2 (COX2), TIAM1