Target List
Antioxidants
Glutathione Peroxidases (GPx)
GPX1GPX2GPX3GPX4GPX5LOC100739163GSTZ1
Peroxiredoxins (TPx)
PRDX1PRDX2PRDX3PRDX4PRDX5PRDX6
Other Peroxidases
CATGP91-PHOX (CYBB)CYGBDUOX1DUOX2EPXLOC100516395 (LPO)MGST3MPOPTGS1PTGS2 (PGHS-2, COX2)TTNTTNLOC100620261 (TTN)
Other Antioxidants
ALBAPOEGSR (GSR)MT-III (MT3)SOD1SOD3TXNRD1TXNRD2VIMP
Reactive Oxygen Species (ROS) Metabolism
Superoxide Dismutases (SOD)
SOD1SOD3
Other Superoxide Metabolism Genes
ALOX12DUOX1DUOX2MT-III (MT3)NCF1NCF2NOS2NOX4NOX5UCP2
Other Reactive Oxygen Species (ROS) Metabolism Genes
AOX1BNIP3EPHX2MPV17SFTPD
Oxidative Stress Responsive Genes
APOECATCCL5 (RANTES)CYGBDHCR24DUOX1DUOX2DUSP1EPXFOXM1FTH1GCLCGCLMGPX1GPX2GPX3GPX4GPX5GSR (GSR)GSSHMOX1HSP70.2 (HSPA1A)KRT1LOC100516395 (LPO)MBL2MPOMSRANQO1NUDT1OXR1OXSR1PDLIM1PRDX2PRDX5PRDX6PRNPRNF7SCARA3SEPP1SIRT2SOD1SQSTM1TTNTTNLOC100620261 (TTN)TXNTXNRD1TXNRD2VIMP
Oxygen Transporters
CYGBMB
Pathway Activity Signature Genes
BAG2FHL2GCLMGLAHMOX1HSP90AA1LHPPLOC100049683 (SLC7A11)LOC100622575 (SPINK1)LOC733635 (AKR1C2)NCOA7NQO1PTGR1TRAPPC6BTXNTXNRD1