PPP1R7 Gene Summary
This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Details
| Type | Protein Coding |
| Official Symbol | PPP1R7 |
| Official Name | protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295] |
| Ensembl ID | ENSG00000115685 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1 regulatory subunit 7 |
| Synonyms | 2310014J01Rik,protein phosphatase 1 regulatory subunit 7,protein phosphatase 1, regulatory subunit 7,SDS22 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- leucine-rich repeat
- occurring C-terminal to leucine-rich repeats
- protein phosphatase 1 regulatory subunit 42
- phosphatase
- Leucine rich repeat
- protein phosphatase regulator
- protein binding
- Leucine Rich repeats (2 copies)
Pathways
Biological processes and signaling networks where the PPP1R7 gene plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- Plasma Membrane
- chromosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the PPP1R7 gene, providing context for its role in the cell.
biological PROCESS
Functions and activities the gene product is involved in
- positive regulation of protein dephosphorylation
cellular COMPONENT
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasm
- chromosome
molecular FUNCTION
What the gene product does at the molecular level
- protein binding
- enzyme regulator activity
- protein phosphatase regulator activity