Target List
HIV Receptors & Natural Ligands
CCL2 (MCP-1), CCL4 (MIP-1B), CCL5 (RANTES), CCR5, CD4, CXCL12 (SDF1), CXCR4
Cellular Cofactors Involved in HIV Infection
Viral Genome Replication
APOBEC3G, CD209, HTATSF1
Inflammatory Response
CCR2, CCR3, CCR4
Antimicrobial Humoral Response
CCR2, YY1
Apoptosis
EP300, LTBR, PTK2B (PYK2)
Cell Cycle
CCNT1, CDK7, CDK9, EP300, RBL2, SMARCB1
Cell Proliferation
CDK7, CDK9, PTK2B (PYK2)
Cell Adhesion Molecules
CCR3, CD209, PTK2B (PYK2)
Transcription Factors & Regulators
APEX1, BCL11B, CCNT1, CREBBP (CBP), EP300, HTATSF1, NFATC1, NFKB1, RBL2, SMARCB1, TFCP2, TSG101, YY1
Other Cellular Cofactors Involved in HIV Infection
BANF1, BTRC (bTrCP), CBX5, CD247, COPS6, ELANE, HCK, LTBR, PPIA, TRIM5, VPS4A, XPO1
Innate Immunity
Humoral Immune Response
IL12B, IL1B, KLRD1, XCL1
Response to Virus
CCL4 (MIP-1B), CCL5 (RANTES), CCL8 (MCP-2), CXCL12 (SDF1), IFNB1, TNF
Inflammatory Response
CCL2 (MCP-1), CCL3 (MIP-1A), CCL4 (MIP-1B), CCL5 (RANTES), CCL8 (MCP-2), CXCL12 (SDF1), IL10, IL1B, CXCL8 (IL8), SERPINA1, TNF
Natural Killer Cell Activation
IFNB1, IL12B, IL2
Defense Response Against Pathogens
CD69, CX3CL1, IFNA1, IFNB1, IFNG
Cell Adhesion Molecules
CCL2 (MCP-1), CCL4 (MIP-1B), CCL5 (RANTES), CD44, CX3CL1, CXCL12 (SDF1), CXCL8 (IL8), SELL (LECAM-1), TNF
Other Innate Immunity Genes
CD74, CR2, IFNG, IL16, MBL2, PRDX1, SERPINC1 (ATIII), SLPI, TGFB1, TNFRSF1B
Immune Evasion
CD4, FCAR, MAP3K5
Cellular Proteins Induced or Activated by HIV Infection
Apoptosis
BAD, BAX, BCL2, CASP3, CASP8 (FLICE), CDKN1A (p21CIP1, WAF1), GADD45A, NFKBIA (IκBα, MAD3), STAT1, TNFSF10 (TRAIL)
Cell Cycle
BAX, BCL2, CDK9, CDKN1A (p21CIP1, WAF1), GADD45A, IRF1, STAT1
Cell Proliferation
BCL2, CDK9, CDKN1A (p21CIP1, WAF1), IRF2
Transcription Factors & Regulators
CDK9, CEBPB, FOS, IRF1, IRF2, NFATC1, NFKBIA (IκBα, MAD3), STAT1, STAT3