Target List
Immune & Inflammatory Responses
Immunostimulatory Factors
Ifng, Il12a, Il12b, Il15, Il2, LOC103694380 (Tnf)
Immunosuppressive Factors
Cd274 (Pdl1), Cd274 (Pdl1), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Ctla4, Cxcl12, Cxcl6, Ido1, Il10, Il13, Il4, Mif (QuantiNova Symbol: LOC103694877), Nos2 (Nos2a, iNos), Pdcd1 (QuantiNova Symbol: NEWGENE_1311658), Ptgs2 (Cox2), Tgfb1, Vegfa
Pro-Inflammatory Genes
Ccl2 (Mcp-1), Ccl20 (Mip-3a), Ifng, Il12a, Il12b, Il17a, Il1a, Il1b, Il2, Il22, Il23a, Il6, LOC103694380 (Tnf), Ptgs2 (Cox2), Tlr4, Vegfa
Anti-Inflammatory Genes
Il10, Il13, Il4, Tgfb1
Enzymatic Modulators of Inflammation & Immunity
Aicda (Aid), Aicda (Aid), Gzma, Gzmb, Ido1, Nos2 (Nos2a, iNos), Ptgs2 (Cox2)
Antigen Presentation
Micb, RT1-A1, RT1-N2
Chemokines
Ccl2 (Mcp-1), Ccl20 (Mip-3a), Ccl21 (Mip-2), Ccl22 (Mdc), Ccl28, Ccl4 (Mip-1b), Ccl5 (Rantes), Cxcl1, Cxcl10 (Inp10), Cxcl11 (I-Tac, Ip-9), Cxcl12, Cxcl2 (Mip-2, Scyb2), Cxcl6, Cxcl9
Interleukins
Il10, Il12a, Il12b, Il13, Il15, Il17a, Il1a, Il1b, Il2, Il22, Il23a, Il4, Il6
Chemokine & Interleukin Receptors
Ackr3, Ccr1, Ccr10, Ccr4, Ccr5, Ccr6, Ccr7, Ccr9, Cxcr1, Cxcr2, Cxcr3, Cxcr4, Cxcr5, Il1r1
Other Cytokines
Kitlg (Scf), Kitlg (Scf), LOC103694380 (Tnf), Mif (QuantiNova Symbol: LOC103694877), Spp1, Tnfsf10 (Trail)
Growth Factors & Receptors
Csf1 (Mcsf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf3 (Gcsf), Egf, Egfr, Igf1, Tgfb1, Vegfa
Signal Transduction
Interferon Signaling
Gbp2, Ifng, Il6, Irf1
Interferon-Responsive Genes
Ccl2 (Mcp-1), Ccl5 (Rantes), Cxcl10 (Inp10), Cxcl9, Gbp2, Irf1, Myd88, Stat1, Tlr3, Tnfsf10 (Trail)
NFκB Targets
Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Ccl2 (Mcp-1), Ccl5 (Rantes), Csf1 (Mcsf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf3 (Gcsf), Ifng, LOC103694380 (Tnf)
STAT Targets
Ccl2 (Mcp-1), Ccl4 (Mip-1b), Ccl5 (Rantes), Csf1 (Mcsf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf3 (Gcsf), Cxcl10 (Inp10), Cxcl11 (I-Tac, Ip-9), Cxcl12, Cxcl9, Il10, Il17a, Il1b, Il23a, Il6, Myc
Toll-Like Receptor Signaling
Myd88, Tlr2, Tlr3, Tlr4, Tlr7
Transcription Factors
Foxp3, Hif1a, Irf1, Myc, Nfkb1, Stat1, Stat3, Tp53 (p53)
Apoptosis
Pro-Apoptotic
Faslg, LOC103694380 (Tnf), Tnfsf10 (Trail), Tp53 (p53)
Anti-Apoptotic
Bcl2, Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Myc, Stat3