Target List
Receptors, Transporters & Channels
Adra1a, Adrb3, Aqp2, Ccr2, Cd28, Ceacam1, Ctla4, Gcgr, Glp1r, Icam1, Il4ra (Cd124), Nsf, Rab4a, Sell (Lecam-1), Slc2a4 (Glut4), Slc14a2, Snap23, Snap25, Stx4a, Stxbp1, Stxbp4, Tnfrsf1a (Tnfr1), Tnfrsf1b, Vamp2, Vamp3, Vapa
Nuclear Receptors
Ppara, Pparg
Metabolic Enzymes
Ace, Acly, Dpp4, Enpp1, Fbp1, G6pc, G6pd2, Gpd1, Gsk3b, Hmox1, Ide, Nos3 (eNOS), Parp1, Pck1, Pfkfb3, Pygl, Sod2
Cytokines & Growth Factors
Agt, Ccl5 (Rantes), Gcg, Ifng, Il6, Il10, Il12b, Ins1, Retn, Tgfb1, Tnf, Vegfa
Signal Transduction
Akt2, Dusp4, Igfbp5, Ikbkb (IKKbeta), Inppl1 (SHIP2), Irs1, Mapk8 (Jnk1), Mapk14 (p38alpha), Pik3cd, Pik3r1 (p85alpha), Ptpn1 (Ptp1b), Trib3 (Skip3)
Transcription Factors
Cebpa, Foxc2, Foxg1, Foxp3, Hnf4a, Pdx1, Neurod1, Nfkb1, Nrf1, Pax4, Ppargc1a (Pgc-1alpha), Srebf1, Hnf1b
Other Diabetes Genes
Serpine1 (Pai-1), Ucp2