Target List
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
COL14A1, COL1A1, COL1A2, COL3A1, COL4A1, COL4A3, COL5A1, COL5A2, COL5A3, VTN
Extracellular Matrix (ECM) Remodeling Enzymes
CTSG, CTSK, CTSL, CTSV, F13A1, F3, FGA, MMP1, MMP2, MMP7, MMP9, PLAT, PLAU, PLAUR, PLG (PLG), SERPINE1 (SERPINE1), TIMP1
Cell Adhesion Molecules
CDH1, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA6, ITGAV, ITGB1, ITGB3, ITGB5, ITGB6
Cytoskeleton Regulators
ACTA2 (α-SMA), ACTC1, RAC1, RHOA, TAGLN
Inflammatory Cytokines & Chemokines
CCL2 (MCP-1), CCL7, CD40LG (TNFSF5), CXCL1, CXCL11, CXCL2, IFNG, IL10, IL1B, IL2, IL4, IL6, MIP-2BETA
Growth Factors
ANGPT1, CSF2 (CSF2), CSF3 (GCSF), CTGF, EGF, FGF10, FGF2, FGF7, HGF, IGF1, MIF, PDGFA, TGFA, TGFB1, TNF, VEGFA
Signal Transduction
TGFβ Signaling
TGFB1, TGFBR3, STAT3
WNT Signaling
CTNNB1, WISP1, WNT5A
Kinases
MAPK1 (ERK2), MAPK3, PTEN
Cell Surface Receptors
EGFR, IL6ST (GP130)
Other Signal Transduction Genes
PTGS2 (COX2)