Target List
Unfolded Protein Binding
Calr, Calr3, Canx, Cct4, Cct6a, Cct6b, Dnajc10, Ero1lb, Hsp90b1, Hspa9, Hspd1, Htra2, Pfdn6, Ahsa2, Dnajc4, Chac1, Dnajb9, Pfdn2, Pfdn5, Dnajb2, Uggt1, Ppil2 (Ppia), Ppil4 (Ppia), Scap, Sec63, Sil1, Tcp1, Tor1a
Endoplasmic Reticulum Protein Folding Quality Control
Edem1, Edem3, Erp44, Ganab, Ganc, Edem2, Uggt2, Serp1, Uggt1, Rpn1
Regulation of Cholesterol Metabolism
Insig1, Insig2, Mbtps1, Mbtps2, Scap, Srebf1, Srebf2
Regulation of Translation
Eif2a, Eif2ak4, Eif2ak3, Serp1, Ppp1r15b
Endoplasmic Reticulum Associated Degradation (ERAD)
Amfr, Derlin-1, Edem1, Herpud1, Htra2, Htra3, Mbtps1, Nploc4, Derl2, Fbxo6, Derl3, Mbtps2, Sel1l, Vimp, Syvn1, Ubxn4
Ubiquitination
Amfr, Edem3, Herpud1, Rnf139, Ube2g2, Ube2j2, Pcgf5, Ufd1l, Sel1l, Ubxn4, Usp14
Transcription Factors
Atf4, Atf6b, Calr, Calr3, Creb3l2, Creb3l3, Ern1, Mbtps1, Atxn3, Ddit3, Pfdn5, Scap, Srebf1, Srebf2, Xbp1
Protein Folding
Calr, Calr3, Canx, Cct4, Cct6a, Cct6b, Dnajc10, Ero1l, Erp44, Hsp90b1, Hspa4l, Hspa9, Hspd1, Pfdn6, Dnajc4, Dnajb9, Pfdn2, Pfdn5, Dnajb2, Uggt1, Ppil2 (Ppia), Ppil4 (Ppia), Sec63, Sil1, Tcp1, Tor1a
Protein Disulfide Isomerization
Dnajc10, Ero1l, Ero1lb, Erp44, Ddit3, Pdia3, Vimp, Srebf1
Heat Shock Proteins
Dnajc10, Dnajc3, Hsp90b1, Hspa1l, Hspa5, Hspa9, Hspd1, Dnajc4, Dnajb9, Hspa4, Dnajb2, Sec63
Apoptosis
Bax, Calr, Calr3, Eif2ak4, Ern1, Htra2, Atxn3, Mapk10, Chac1, Ddit3, Eif2ak3, Mapk8, Mapk9, Pdia3, Ppp1r15b, Vimp