Details
| Type | Protein Coding |
| Official Symbol | PTEN |
| Official Name | phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588] |
| Ensembl ID | ENSG00000284792 |
| Bio databases IDs | |
| Aliases | phosphatase and tensin homolog |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the PTEN gene in human plays a role, providing insight into its function and relevance in health or disease.
- Autophagy
- B Cell Receptor Signaling
- Cancer Drug Resistance By Drug Efflux
- Chronic Myeloid Leukemia Signaling
- Endometrial Cancer Signaling
- Epithelial Adherens Junction Signaling
- ErbB2-ErbB3 Signaling
- Estrogen Receptor Signaling
- FAK Signaling
- Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes
- Glioblastoma Multiforme Signaling
- Glioma Signaling
- HER-2 Signaling in Breast Cancer
- Hereditary Breast Cancer Signaling
- Hypoxia Signaling in the Cardiovascular System
- iCOS-iCOSL Signaling in T Helper Cells
- IL-17A Signaling in Airway Cells
- ILK Signaling
- Insulin Receptor Signaling
- Integrin Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- COWDEN SYNDROME 1
- GLIOMA SUSCEPTIBILITY 2
- MACROCEPHALY/AUTISM SYNDROME
- MENINGIOMA FAMILIAL SUSCEPTIBILITY TO
- Prostate Cancer
- Proteus syndrome
- Pten Hamartoma Tumor Syndrome