Target List
T-Cell Activation
T-Cell Activation Regulators
CD2, CD276, CD47, DPP4, CD3D, CD3E, CD3G, CD4, CD7, CD80, CD86, CD8A, CD8B, FOXP3, ICOSLG, IRF4, LAG3, LCK, MAP3K7 (TAK1), MICB, NCK1, TNFSF14, VAV1
T-Cell Proliferation
CD28, CD3E, ICOSLG, IL1B, IL10, IL12B, IL18, NCK1, RIPK2, TNFSF14
T-Cell Differentiation
ADA, APC, BCL2, BLM, CD1D, CD2, CD27 (TNFRSF7), CD4, CD80, CD86, EGR1, IL12B, IL15, IL2, IRF4, NOS2 (iNOS), PTPRC, SOCS1
T-Cell Polarization
CCL3 (MIP-1A), CCR1, CCR2, CCR3, CCR4, CCR5, CD274 (PD-L1), CD274 (PD-L1), CD28, CD4, CD40LG, CSF2 (GM-CSF), CXCR3, CXCR4, IFNG, IL12A, IL12RB1, IL12RB2, IL18R1, IL2, IL4, IL4R (CD124), IL5, TGFB1
Th1 & Th2 Developmental Regulators
CD2, CD40 (TNFRSF5), CD5, CD7, CSF2 (GM-CSF), IFNG, IL10, IL12A, IL13, IL3, IL4, IL5, TLR2, TLR4, TLR9
Th1 & Th2 Differentiation
CD28, CD40 (TNFRSF5), CD40LG, CD86, IFNG, IL12A, IL12B, IL12RB1, IL12RB2, IL18, IL18R1, IL2, IL2RA (CD25), IL4, IL4R (CD124), IL6
B-Cell Activation
Antigen-Dependent B-Cell Activation
CD28, CD4, CD40 (TNFRSF5), CD40LG, CD80, FAS, FASLG (TNFSF6), IL10, IL2, IL4
Other B-Cell Activation Genes
ADA, CXCR5, ICOSLG, IL6, IL7, MS4A1, TGFB1
B-Cell Proliferation
BCL2, CD27 (TNFRSF7), CD40 (TNFRSF5), CD81, IL10, IL7, PTPRC
B-Cell Differentiation
ADA, AICDA (AID), AICDA (AID), BLNK, CD27 (TNFRSF7), IL10, IL11, IL4, RAG1
Activation of Other Immune Cells
Macrophage Activation
IL13, IL4, TLR1, TLR4, TLR6
Neutrophil Activation
CXCL8 (IL8)
Natural Killer Cell Activation
CD2, IL12A, IL12B, IL2
Leukocyte Activation
CX3CL1