Target List
Receptors Involved in Phagocytosis
AGER, CD14, CD36, CLEC7A (DECTIN1), COLEC12, CR1, CRP, FAS, FCER1G, FCGR1A, FCGR2A, FCGR2B, IL1RL1 (ST2), ITGAM, ITGAV, ITGB2, MARCO, MFGE8, MYD88, PECAM1, TICAM1 (TRIF), TLR3, TLR9
Recognition & Engulfment
ANXA1, C3, CD44, CD47, CEACAM3, CSF1 (MCSF), CSF2 (GM-CSF), ELMO1, GULP1, IFNG, MBL2, MCOLN3, MIF, SCARB1, SIGLEC1, SIGLEC11, SIRPB1, TGM2, TNF, WNT5A
Phagosome Maturation
CNN2, PLD1, RAB5A, RAB7A, STX18, VAMP7, WAS
Phagosome Processing
CALR, CRK, CYP2S1, NOD1 (CARD4), PLA2G4A, PLA2G5, PLD2, SERPINE1 (PAI-1), SFTPD, STAB2, TNFSF11 (RANKL)
Signal Transduction
ADIPOQ (ACRP30), AXL, CLIC4, CSK, DOCK1, DOCK2, FYN, LYN, MAPK14 (p38ALPHA), MERTK, MSN, PIP5K1A, PRKCE, PROS1, PTEN, RAC1, RAC2, RALA, RALB, RAPGEF3, RHOA, SYK, VAV1