QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel

Central Nervous System Cancers

Anaplastic Glial Tumors

CDKN2A (P16INK4A)CDKN2B (p15INK4b)PTENRB1TP53 (p53)

Astrocytomas

APCATRXBRAFCDKN2A (P16INK4A)CDKN2B (p15INK4b)CDKN2B-AS1CHEK2 (RAD53)FGFR1HIPK2HRASIDH1MSH2MYBNF1PALB2PTPN11RB1SDHATP53 (p53)TSC1

Atypical Teratoid Rhabdoid Tumors

SMARCA4SMARCB1

Craniopharyngiomas

BRAFCTNNB1

Ependymomas

CDKN2A (P16INK4A)ERBB2 (HER-2, NEU)MEN1NF2TP53 (p53)

Ganglioneuromas

ALKPHOX2B

Gliomas

ACVR1 (ALK2)ADGRB3ATRXBRAFBRCA2BRIP1CDKN2A (P16INK4A)CHD2CHEK2 (RAD53)CICEGFR (ERBB1)EP300FGFR1FLT1 (VEGFR1)H3-3AIDH1IRS2MDM4MYBMYCNNF1NSD2PDGFRAPIK3CA (p110-alpha)POT1PTENSTYK1TP53 (p53)

Hereditary Paraganglioma-Pheochromocytoma Syndrome

MAXSDHAF2SDHBSDHCSDHDTMEM127

Intercranial Ependymomas

CDKN2A (P16INK4A)CDKN2B (p15INK4b)

Lynch Syndrome

EPCAMMLH1MSH2MSH6PMS2

Meningiomas

CDKN2A (P16INK4A)CDKN2B (p15INK4b)G6PDMN1NF2PDGFBPTENSMARCE1SUFU

Neuroblastomas

ALKBRCA1BRCA2DICER1EZH2HRASKIF1BNRASPHOX2BPTCH1PTPN11SMARCA4TP53 (p53)

Neurofibromas

EPCAMMLH1MSH2MSH6NF1PMS2

Neurofibromatosis

NF1NF2

Oligodendrogliomas

CDKN2A (P16INK4A)CDKN2B (p15INK4b)IDH1MSH2RB1

Tuberous Sclerosis Complex

TSC1TSC2

Other Central Nervous System Cancer Genes

AIPCDKN1B (P27KIP1)EPHB2PRKAR1AVHL

Colorectal Cancers

Adenocarcinomas

APCATMAXIN2BMPR1A (ALK3)BRAFBRCA1BRCA2CHEK2 (RAD53)EP300FLCNMLH1MLH3MSH2MSH3MSH6MUTYHNRASPALB2PMS1PMS2POLD1POLEPTENRNF43SMAD4 (MADH4)STK11 (LKB1)TGFBR2TP53 (p53)

Colorectal Cancer Susceptibility

CCND1GALNT12POLD1POLESMAD7

Familial Adenomatous Polyposis

APCMSH3MUTYHNTHL1POLD1POLE

Hereditary Mixed Polyposis Syndrome

BMPR1A (ALK3)GREM1

Hereditary Nonpolyposis

BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2

Hereditary Polyposis Syndrome

BMPR1A (ALK3)GREM1

Juvenile Polyposis Syndrome

BMPR1A (ALK3)SMAD4 (MADH4)

Lynch Syndrome

BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2

Metastatic Colorectal Cancers

ATMBRAFNRAS

Muir-Torre Syndrome

MLH1MSH2

Other Colorectal Cancer Genes

AURKABLMCDH1 (E-Cadherin)PKHD1PLA2G2ARB1RPS20SEMA4ATLR2XRCC2

Gastric Cancers

Gastrointestinal Stromal Tumors (GIST)

KIT (CD117)NF1PDGFRASDHBSDHCSDHDTMEM127

Lynch Syndrome

EPCAMMLH1MSH2MSH6PMS2

Multiple Endocrine Neoplasia

CDKN1B (P27KIP1)MEN1

Other Gastric Cancer Genes

APCATMBMPR1A (ALK3)CDH1 (E-Cadherin)CHEK2 (RAD53)CTNNA1KRASSMAD4 (MADH4)STK11 (LKB1)TP53 (p53)

Hematological Malignancies

Eosinophilia

CR2JAK1

Lymphoproliferative Disorders

PLAASH2D1AXIAP

Mastocytosis

DNMT3AIDH2KIT (CD117)NRASRUNX1 (AML1)

Multiple Myeloma

ATMCCND1IDH1IDH2KIT (CD117)LIG4NRASTP53 (p53)

Myelodysplastic Syndromes

CEBPADNMT3AGATA2GNB1IDH1IDH2KIT (CD117)MPLMSH6NF1NRASRUNX1 (AML1)SMAD9TERCTERTTP53 (p53)

Myelofibrosis

DNMT3AIDH1IDH2MPLNF1NRASTP53 (p53)

Myeloproliferative Neoplasms

DNMT3AIDH1IDH2MPLRUNX1 (AML1)SH2B3TP53 (p53)

Polycythemia Vera

DNMT3AIDH1NRASTP53 (p53)

Thrombocythemia

IDH2MPLSH2B3THPOTP53 (p53)

Other Hematological Malignancies Genes

BLMEPCAMHRASMLH1MSH2NBNPMS2

Hereditary Breast & Ovarian Cancers (HBOC)

Familial Breast-Ovarian Cancer Susceptibility

BRCA1BRCA2FGFR2MAP3K1 (MEKK1)RAD51CRAD51DTOX3

Breast Cancer Carcinomas

ATMBARD1BRCA1BRCA2BRIP1CHEK2 (RAD53)ERBB2 (HER-2, NEU)ESR1 (ERα)MLH1MSH2MSH6PALB2PIK3CA (p110-alpha)PMS2RAD51CRAD51D

Breast Cancer Ductal Carcinomas

CDH1 (E-Cadherin)FGFR2MRE11NBNSTK11 (LKB1)TP53 (p53)

Breast Cancer Susceptibility

BARD1BRCA2PALB2RECQLXRCC3

Metastatic Breast Cancers

BRCA1BRCA2ERBB2 (HER-2, NEU)ESR1 (ERα)NF1PALB2PIK3CA (p110-alpha)PTEN

Other Breast Cancer Genes

APCAXIN2SDHBSMARCA4TSHR

Ovarian Cancer Epithelial Carcinomas

ABRAXAS1ATMBARD1BRCA1BRCA2BRIP1CHEK2 (RAD53)ERBB2 (HER-2, NEU)MRE11NBNNF1PALB2PIK3CA (p110-alpha)PTENRAD51CRAD51DTP53 (p53)

Ovarian Cancer Mixed Adenosquamous Carcinomas

BLMCDH1 (E-Cadherin)DICER1FANCCFANCMFGFR2RAD50RAD51SMARCA4STK11 (LKB1)

Other Ovarian Cancer Genes

MLH1RECQLRINT1XRCC2

Uterine Serous Carcinomas

BLMCDH1 (E-Cadherin)DICER1FANCCFANCMFGFR2RAD50RAD51SMARCA4

Lynch Syndrome

EPCAMMLH1MSH2MSH6PMS2

Other Hereditary Breast & Ovarian Cancer Genes

HMMRMUTYHNQO2PGRPHBPOLD1PRKAR1A

Kidney Cancers

Hamartomas

CDC73DIS3L2

Lynch Syndrome

EPCAMMLH1MSH6PMS2

Nephroblastomas

CDKN1C (p57Kip2)DIS3L2TRIM28

Papillary Renal Cell Carcinomas

FHMET

Renal Cell Carcinomas

BAP1BRAFFGFR3FHFLCNHNF1AHNF1BMETMITFMSH2MTORNRASPIK3CA (p110-alpha)PTENSDHASDHBSDHCSDHDTMEM127TP53 (p53)VHL

Rhabdoid Tumors

SMARCA4SMARCB1

Tuberous Sclerosis Complex

TSC1TSC2

Wilms Tumors

BRAFBRCA2CDC73CDKN1C (p57Kip2)DICER1DIS3L2FZD6GPC3PAX6RESTVHLWT1

Other Kidney Cancer Genes

BUB1B

Myeloid Neoplasms

Acute Megakaryoblastic Leukemia (AMKL)

ERGGATA1JAK2METMPLOLIG2RUNX1 (AML1)SMOTMPRSS2

Acute Myeloid Leukemia (AML)

BRCA2CEBPACHIC2DDX41DNMT3AETV6FLT3GATA1GATA2IDH1IDH2IKZF1IKZF2IKZF3JAK2KIT (CD117)KRASLPPMLLT10NRASPTPN11RB1RUNX1 (AML1)SH3GL1TERTTP53 (p53)WT1

Acute Promyelocytic Leukemia (APML; APL)

CEBPARUNX1 (AML1)

Atypical Chronic Myeloid Leukemia (aCML)

CBLCEBPAEZH2FLT3JAK2KRASNRASRUNX1 (AML1)SETBP1

B Cell Acute Lymphoblastic Leukemia (B-ALL)

IKZF1JAK1JAK2PAX5

Chronic Lymphocytic Leukemia (CLL)

BRAFGNB1NOTCH1NRASPTPN11TP53 (p53)

Chronic Myeloid Leukemia (CML)

BRAFCBLCREBBP (CBP)DNMT3AEZH2IDH1IDH2IKZF1JAK2KRASNRASRUNX1 (AML1)TP53 (p53)WT1

Chronic Myelomonocytic Leukemia (CMML)

CBLCEBPADNMT3AEZH2FLT3IDH1IDH2JAK2KIT (CD117)KRASMPLNF1NRASPHF6PTPN11RUNX1 (AML1)SETBP1TP53 (p53)

Hairy Cell Leukemia

BRAFTP53 (p53)

Juvenile Myelomonocytic Leukemia

CBLKRASNF1NRASPTPN11

T Cell Acute Lymphoblastic Leukemia (T-ALL)

FBXW7NOTCH1

Other Leukemia Genes

APCATMCDH1 (E-Cadherin)DICER1DNAJC21ERBB3ERCC2 (XPD)ERCC4KCNQ1MSH2MSH6MUTYHNBNNSD1RECQL4RETSOS1STK11 (LKB1)TSC2

Acute Lymphoblastic Lymphomas

CDKN2A (P16INK4A)CDKN2B (p15INK4b)NOTCH1TP53 (p53)

B Cell Lymphomas

BRAFCHEK2 (RAD53)EZH2TP53 (p53)

Follicular Lymphomas

CREBBP (CBP)EP300EZH2

Non-Hodgkin Lymphomas

BRAFNRASPIK3CA (p110-alpha)TP53 (p53)

T Cell Lymphomas

ATMDNMT3AHAVCR2IDH1IDH2JAK1JAK3SETD2

Other Lymphoma Genes

B2MBRCA2CEBPAKIT (CD117)KLHDC8BMSH2MSH6MUTYHPRF1PTPN11RB1RECQL4RETSTK11 (LKB1)TSC2

Myelodysplastic Syndromes

CBLCEBPADDX41DNMT3AETV6EZH2FLT3GATA2GNB1IDH1IDH2JAK2JAK3KIT (CD117)KRASMPLNF1NRASPHF6PTPN11RUNX1 (AML1)SETBP1TERCTERTTP53 (p53)WT1

Myeloproliferative Neoplasms

CBLDNMT3AEZH2IDH1IDH2JAK2MPLRUNX1 (AML1)SH2B3TP53 (p53)

Essential Thrombocythemia

CBLIDH2JAK2MPLTP53 (p53)

Fanconi Anemia

FANCAFANCBFANCD2FANCEFANCFFANCGFANCIFANCMSLX4

Mastocytosis

CBLEZH2IDH2JAK2KIT (CD117)KRASNRASRUNX1 (AML1)

Multiple Myeloma

ATMBRAFBRCA2CHEK2 (RAD53)FANCLIDH1IDH2KIT (CD117)KRASMETNRASRETTP53 (p53)

Polycythemia Vera

DNMT3AEZH2IDH1JAK2NRASTP53 (p53)

Primary Myelofibrosis

CBLDNMT3AEZH2IDH1IDH2JAK2MPLNF1NRASSETBP1TP53 (p53)

Systemic Mastocytosis

CBLDNMT3AETV6EZH2IDH2JAK2KIT (CD117)KRASNRASRUNX1 (AML1)SETBP1

Pancreatic Cancers

Adenocarcinomas

ATMBRCA1BRCA2CDKN2A (P16INK4A)CFTREPCAMFANCCMLH1MSH2MSH6PALB2PALLDPMS2PRSS1SMAD4 (MADH4)SPINK1STK11 (LKB1)TP53 (p53)

Adenomas

TSC1TSC2

Familial Pancreatic Cancers

ATMBRCA2CDKN2A (P16INK4A)PALB2

Hereditary Pancreatitis

CFTRCTRCPRSS1PRSS2SPINK1

Lynch Syndrome

EPCAMMLH1MSH2MSH6PMS2

Multiple Endocrine Neoplasia

CDKN1B (P27KIP1)MEN1

Pancreatic Cancer Susceptibility

BRCA1BRCA2PALB2PALLDRABL3

Other Pancreatic Cancer Genes

APCBMPR1A (ALK3)CASRCDK4CPA1NF1VHL

Pediatric Cancers

Craniopharyngiomas

APCSMARCA4SUFUTSC1

Embryonal Rhabdomyosarcomas

CARD11CTNNB1FGFR4HRASKRASMDM2MDM4NF1NRASPIK3CA (p110-alpha)RARATP53 (p53)

Ependymomas

Ewing's Sarcoma

Germ Cell Tumors

Hepatoblastomas

Hepatocellular Carcinomas

APCCREBBP (CBP)CTNNB1IDH1KRASMETNRASPIK3CA (p110-alpha)TERTTP53 (p53)

Lynch Syndrome

EPCAMMLH1PMS2

Nephroblastomas

BRCA2CDKN1C (p57Kip2)DIS3L2PAX6POU6F2RESTSMARCB1WT1

Neuroblastomas

ALKPHOX2BPTCH1

Osteosarcomas

ATRXCDKN2A (P16INK4A)CHEK2 (RAD53)RB1RECQL4TP53 (p53)TSC2

Retinoblastomas

APCCEBPAMAXRB1STK11 (LKB1)TSC2

Rhabdomyosarcomas

BRCA1DICER1FOXO1MSH2PAX3PAX7

Other Pediatric Cancer Genes

CDC73PRKAR1AVHL

Prostate Cancers

Adenocarcinomas

ARBRIP1CHEK2 (RAD53)NBNPTENRAD51CRAD51DTP53 (p53)

Advanced Prostate Cancers

ATMBRCA1BRCA2PALB2PTEN

Lynch Syndrome

EPCAMMLH1MSH2MSH6PMS2

Other Prostate Cancer Genes

CDH1 (E-Cadherin)EHBP1ELAC2HOXB13MSMBRNASEL

Skin Cancers

Cutaneous Melanomas

BAP1CDK4CDKN2A (P16INK4A)MC1RMITFPOT1XRCC3

Malignant Melanoma Susceptibility

CDK4CDKN2A (P16INK4A)MC1RMITFPOT1TERTXRCC3

Malignant Melanomas

CDK4CDKN2A (P16INK4A)MC1RMITFPOT1XRCC3

Melanomas

BRAFBRCA1BRCA2CDK4CDKN2A (P16INK4A)CDKN2B-AS1CREBBP (CBP)IDH1KIT (CD117)KRASMAP2K1MAP2K2 (MEK2)MC1RMITFNRASPIK3CA (p110-alpha)POT1PTENRAF1RB1TERTTP53 (p53)TYR

Uveal Melanomas

BAP1BRCA2CDKN2A (P16INK4A)CDKN2B (p15INK4b)

Xeroderma Pigmentosum

DDB2ERCC2 (XPD)ERCC3 (XPB)ERCC4ERCC5POLHXPAXPC

Other Skin Cancer Genes

ATRCYLDFHFLCNPRKAR1APTCH2

QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel

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QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel

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Select a variant to see the price