Target List
Somatic Stem Cell Maintenance
CDX2, NANOG, POU5F1 (OCT4), SOX2
Placental Development
CDX2, HAND1, PPARG, SP1, VDR
Induced Pluripotent & Embryonic Stem Cells
NANOG, POU5F1 (OCT4), SOX2, STAT3
Axis / Symmetry / Segmentation
CDX2, DLX1, DLX2, FOXA2 (HNF3B), HOXA11, HOXA2, HOXA3, HOXA7, HOXA9, HOXA10, HOXB1, HOXB3, HOXB5, HOXB8, HOXC10, HOXC4, HOXC5, HOXC6, HOXC9, HOXD10, HOXD4, LMX1B, NEUROD1, NOTCH2, NR2F2, PAX1, PITX2, SMAD2 (MADH2), TBX5, TDGF1, ZIC1
Embryonic Development
CDX2, DLX1, DLX2, FOXA2 (HNF3B), GATA6, GLI2, HAND1, HOXA11, HOXA2, HOXA3, HOXA7, HOXA9, HOXA10, HOXB1, HOXB3, HOXB5, HOXB8, HOXC10, HOXC4, HOXC5, HOXC6, HOXC9, HOXD1, HOXD10, HOXD4, KLF4, LMX1B, MSX2, NANOG, NEUROD1, NOTCH2, PAX1, SIX2, SMAD2 (MADH2), SOX2, SP1, TBX5, TDGF1, ZFPM2, ZIC1
Ectoderm, Endoderm & Mesoderm Formation & Differentiation
FOXA2 (HNF3B), GATA6, HAND1, HOXA7, HOXB13, ISL1, KLF4, SMAD2 (MADH2), SOX9
Organ Morphogenesis
CDX2, DLX1, DLX2, GLI2, HAND1, HOXA11, HOXA2, HOXA3, HOXA7, HOXB1, HOXB13, HOXB3, HOXB5, HOXB8, HOXC4, HOXC9, HOXD10, HOXD4, ISL1, JUN, KLF4, MSX2, MYC, NEUROD1, NOTCH2, NR2F2, PAX1, PAX5, PAX6, PITX2, PITX3, PPARG, RUNX1 (AML1), SIX2, SMAD2 (MADH2), SOX2, SOX9, SP1, STAT3, TBX5, TDGF1, VDR, WT1, ZFPM2, ZIC1
Angiogenesis
CDX2, HAND1, JUN, NR2F2, RUNX1 (AML1), WT1
Neurogenesis
DLX1, DLX2, DNMT3B, FOXA1, FOXA2 (HNF3B), FOXP3, GLI2, HOXA2, HOXC10, HOXD10, ISL1, LMX1B, NEUROD1, NKX2-2, NR2F2, OLIG2, PAX6, PITX3, POU4F1, POU4F2, PPARG, SOX2, STAT3, TLX3
Hematopoiesis
RB1, RUNX1 (AML1), SOX6, SP1, STAT1
Osteogenesis
GLI2, HOXA2, SOX2, SP1
Other Stem Cell Transcription Factors
DACH1, EGR3, ESR1 (ERα), EZH2, FOXP1, FOXP2, GATA1, HOXC12, HTR7, IRX4, KLF2, LIN28B, NFATC1, PAX9, PCNA, TERT, WRN