Target List
Angiogenesis
ANGPT1, ANGPT2, CCL2 (MCP-1), FGF2 (BFGF), FLT1 (VEGFR1), KDR (VEGFR3), PGF, SERPINF1, TEK (TIE-2, TIE2), VEGFC
Apoptosis
APAF1, BCL2L11, BIRC3 (c-IAP2), CASP2, CASP7, CASP9, CFLAR (CASPER), FASLG (TNFSF6), NOL3, XIAP
Cell Cycle
AURKA, CCND2, CCND3, CDC20, E2F4, MCM2, MKI67, SKP2, STMN1, WEE1
Cellular Senescence
BMI1, ETS2, IGFBP3, IGFBP5, IGFBP7, MAP2K1, MAP2K3 (MEK3), MAPK14 (p38ALPHA), SERPINB2 (PAI-2), SOD1, TBX2
DNA Damage & Repair
DDB2, DDIT3 (GADD153, CHOP), ERCC3 (XPB), ERCC5, GADD45G, LIG4, POLB, PPP1R15A (GADD34)
Epithelial-to-Mesenchymal Transition (EMT)
CDH2 (N-Cadherin), DSP, FOXC2, GSC, KRT14, OCLN, SNAI1 (SNAIL), SNAI2, SNAI3, SOX10
Hypoxia Signaling
ADM, ARNT, CA9, EPO, HMOX1, LDHA, SLC2A1
Metabolism
ACLY, ACSL4, ATP5F1A, COX5A, CPT2, G6PD, GPD2, LPL, PFKL, UQCRFS1
Telomeres & Telomerase
DKC1, PINX1, TEP1, TERF1, TERF2IP, TINF2, TNKS (TIN1), TNKS2