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IL-15 Production

Interleukin 15 (IL-15) belongs to the 4-α-helix bundle family of glycoprotein cytokines that include IL-2, IL-3, IL-4 and IL-21. It exerts profounds effects on the proliferation, survival and differentiation of NK cells and T cells. IL-15 is produced in a variety of cell types like monocytes, dendritic cells, macrophages, keratinocytes, fibroblasts, and nerve cells. Its production is under complex control with regulation occurring at the level of transcription, translation, intracellular trafficking and translocation. (Upgraded 01/2020)...

IL-15 Production

Pathway Summary

Interleukin 15 (IL-15) belongs to the 4-α-helix bundle family of glycoprotein cytokines that include IL-2, IL-3, IL-4 and IL-21. It exerts profounds effects on the proliferation, survival and differentiation of NK cells and T cells. IL-15 is produced in a variety of cell types like monocytes, dendritic cells, macrophages, keratinocytes, fibroblasts, and nerve cells. Its production is under complex control with regulation occurring at the level of transcription, translation, intracellular trafficking and translocation. (Upgraded 01/2020)

IL-15 Production Genes list

Explore Genes related to IL-15 Production
AATK
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Human
apoptosis associated tyrosine kinase
ABL1
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Human
ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2
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Human
ABL proto-oncogene 2, non-receptor tyrosine kinase
ALK
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Human
ALK receptor tyrosine kinase
AXL
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Human
AXL receptor tyrosine kinase
BLK
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Human
BLK proto-oncogene, Src family tyrosine kinase
BMX
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Human
BMX non-receptor tyrosine kinase
BTK
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Human
Bruton tyrosine kinase
CLK1
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Human
CDC like kinase 1
CLK2
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Human
CDC like kinase 2
CLK3
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Human
CDC like kinase 3
CLK4
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Human
CDC like kinase 4
CSF1R
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Human
colony stimulating factor 1 receptor
CSF2RA
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Human
colony stimulating factor 2 receptor subunit alpha
CSK
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Human
C-terminal Src kinase
DDR1
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Human
discoidin domain receptor tyrosine kinase 1
DDR2
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Human
discoidin domain receptor tyrosine kinase 2
DSTYK
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Human
dual serine/threonine and tyrosine protein kinase
DYRK1A
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Human
dual specificity tyrosine phosphorylation regulated kinase 1A
DYRK3
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Human
dual specificity tyrosine phosphorylation regulated kinase 3
DYRK4
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Human
dual specificity tyrosine phosphorylation regulated kinase 4
EGFR
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Human
epidermal growth factor receptor
EPHA1
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Human
EPH receptor A1
EPHA2
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Human
EPH receptor A2
EPHA3
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Human
EPH receptor A3
EPHA4
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Human
EPH receptor A4
EPHA5
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Human
EPH receptor A5
EPHA6
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Human
EPH receptor A6
EPHA8
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Human
EPH receptor A8
EPHB1
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Human
EPH receptor B1
EPHB2
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Human
EPH receptor B2
EPHB3
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Human
EPH receptor B3
EPHB4
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Human
EPH receptor B4
ERBB2
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Human
erb-b2 receptor tyrosine kinase 2
ERBB3
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Human
erb-b2 receptor tyrosine kinase 3
ERBB4
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Human
erb-b2 receptor tyrosine kinase 4
FER
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Human
FER tyrosine kinase
FES
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Human
FES proto-oncogene, tyrosine kinase
FGFR1
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Human
fibroblast growth factor receptor 1
FGFR2
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Human
fibroblast growth factor receptor 2
FGFR3
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Human
fibroblast growth factor receptor 3
FGFR4
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Human
fibroblast growth factor receptor 4
FGR
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Human
FGR proto-oncogene, Src family tyrosine kinase
FLT1
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Human
fms related receptor tyrosine kinase 1
FLT3LG
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Human
fms related receptor tyrosine kinase 3 ligand
FLT4
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Human
fms related receptor tyrosine kinase 4
FRK
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Human
fyn related Src family tyrosine kinase
FYN
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Human
FYN proto-oncogene, Src family tyrosine kinase
HCK
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Human
HCK proto-oncogene, Src family tyrosine kinase
IFNA21
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Human
interferon alpha 21
IFNA5
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Human
interferon alpha 5
IFNB1
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Human
interferon beta 1
IGF1R
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Human
insulin like growth factor 1 receptor
IL15
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Human
interleukin 15
IL6
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Human
interleukin 6
INSR
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Human
insulin receptor
IRF1
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Human
interferon regulatory factor 1
IRF3
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Human
interferon regulatory factor 3
ITK
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Human
IL2 inducible T cell kinase
JAK1
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Human
Janus kinase 1
JAK2
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Human
Janus kinase 2
JAK3
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Human
Janus kinase 3
KDR
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Human
kinase insert domain receptor
KIT
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Human
KIT proto-oncogene, receptor tyrosine kinase
LCK
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Human
LCK proto-oncogene, Src family tyrosine kinase
LMTK2
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Human
lemur tyrosine kinase 2
LMTK3
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Human
lemur tyrosine kinase 3
LTK
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Human
leukocyte receptor tyrosine kinase
LYN
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Human
LYN proto-oncogene, Src family tyrosine kinase
MAP2K1
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Human
mitogen-activated protein kinase kinase 1
MAP2K3
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Human
mitogen-activated protein kinase kinase 3
MAP2K4
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Human
mitogen-activated protein kinase kinase 4
MAP2K5
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Human
mitogen-activated protein kinase kinase 5
MAP2K6
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Human
mitogen-activated protein kinase kinase 6
MAP2K7
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Human
mitogen-activated protein kinase kinase 7
MAP3K11
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Human
mitogen-activated protein kinase kinase kinase 11
MATK
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Human
megakaryocyte-associated tyrosine kinase
MERTK
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Human
MER proto-oncogene, tyrosine kinase
MET
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Human
MET proto-oncogene, receptor tyrosine kinase
MST1R
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Human
macrophage stimulating 1 receptor
MUSK
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Human
muscle associated receptor tyrosine kinase
NFKB1
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Human
nuclear factor kappa B subunit 1
NFKB2
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Human
nuclear factor kappa B subunit 2
NTRK1
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Human
neurotrophic receptor tyrosine kinase 1
NTRK2
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Human
neurotrophic receptor tyrosine kinase 2
NTRK3
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Human
neurotrophic receptor tyrosine kinase 3
PDGFRA
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Human
platelet derived growth factor receptor alpha
PDGFRB
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Human
platelet derived growth factor receptor beta
PEAK1
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Human
pseudopodium enriched atypical kinase 1
PRKCI
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Human
protein kinase C iota
PRKCZ
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Human
protein kinase C zeta
PTK2
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Human
protein tyrosine kinase 2
PTK2B
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Human
protein tyrosine kinase 2 beta
PTK6
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Human
protein tyrosine kinase 6
PTK7
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Human
protein tyrosine kinase 7 (inactive)
REL
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Human
REL proto-oncogene, NF-kB subunit
RELA
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Human
RELA proto-oncogene, NF-kB subunit
RELB
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Human
RELB proto-oncogene, NF-kB subunit
RET
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Human
ret proto-oncogene
ROR1
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Human
receptor tyrosine kinase like orphan receptor 1
ROR2
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Human
receptor tyrosine kinase like orphan receptor 2
ROS1
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Human
ROS proto-oncogene 1, receptor tyrosine kinase
RYK
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Human
receptor like tyrosine kinase
SRC
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Human
SRC proto-oncogene, non-receptor tyrosine kinase
SRMS
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Human
src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STAT1
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Human
signal transducer and activator of transcription 1
STYK1
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Human
serine/threonine/tyrosine kinase 1
SYK
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Human
spleen associated tyrosine kinase
TEC
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Human
tec protein tyrosine kinase
TEK
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Human
TEK receptor tyrosine kinase
TIE1
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Human
tyrosine kinase with immunoglobulin like and EGF like domains 1
TNK1
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Human
tyrosine kinase non receptor 1
TNK2
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Human
tyrosine kinase non receptor 2
TWF1
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Human
twinfilin actin binding protein 1
TXK
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Human
TXK tyrosine kinase
TYK2
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Human
tyrosine kinase 2
TYRO3
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Human
TYRO3 protein tyrosine kinase
YES1
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Human
YES proto-oncogene 1, Src family tyrosine kinase
ZAP70
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Human
zeta chain of T cell receptor associated protein kinase 70

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RT² Profiler™ PCR Array Human Cytokines & Chemokines
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QuantiNova LNA Probe PCR Focus Panel Human Cytokines & Chemokines
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QuantiNova LNA PCR Focus Panel Human Cytokines & Chemokines
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