Target List
Cell Surface Receptors
Cadherins
CDH1 (E-Cadherin), CDH2 (N-Cadherin), CDH3, CDH4, CDH5
Desmocollins & Desmogleins
DSC1, DSC2, DSC3, DSG1, DSG2, DSG3, DSG4
Nectins
NECTIN1, NECTIN2, NECTIN3, NECTIN4
Notch Signaling
DLL1 (DELTA1), NOTCH1, NOTCH2, NOTCH3, NOTCH4
Desmosomes
CDSN, DSP, JUP (CTNNG), PKP1, PKP2, PKP3, PKP4, PNN, PPL
Junction Associated Proteins
AFDN, AJAP1, CTNND1, DLG5, P2RX6, PARD3, PERP, TJP1, VEZT
Catenins
ARVCF, CTNNA1, CTNNA2, CTNNA3, CTNNB1, CTNND1
Cytoskeleton Regulators
ACTN1, ACTN2, ACTN3, ACTN4, ANAPC1, BAIAP2, CDC27, EXOC2, FARP2, FLNA, FLNB, LMO7, MAPRE1, MAPRE2, NME1 (NM23), PARD3, SORBS1, SSX2IP, TLN1, TLN2, VCL, WAS, WASF1, WASL, ZYX
Endocytosis
DNM1, DNM2, HGS, LMO7, PIK3CG, PLPP3, SORBS1
Protein Kinase Signaling
CSNK2A1, CSNK2A2, CSNK2B, DLG5
G-Protein Signaling
AFDN, ARF6, CDC42, DOCK4, FARP2, IQGAP1, RAC1, RALA, RHOA
Ubiquitin-Protein Ligases (E3)
ANAPC1, CBLL1