Target List
Stem Cell Specific Markers
Regulation of the Cell Cycle
APC, AXIN1, CCNA2, CCND1, CCND2, CCNE1, CDC42, CDK1, EP300, FGF1, FGF2 (BFGF), FGF3, FGF4, MYC, NOTCH2, PARD6A, RB1
Chromatin Modification Enzymes & Remodeling Factors
HDAC2, KAT2A, KAT7, KAT8, RB1, TERT
Symmetric & Asymmetric Cell Division
DHH, NOTCH1, NOTCH2, NUMB, PARD6A
Self-Renewal Markers
HSPA9, KAT7, KAT8, NEUROG2, SOX1, SOX2
Cytokines & Growth Factors
BMP1, BMP2, BMP3, CXCL12 (SDF1), FGF1, FGF2 (BFGF), FGF3, FGF4, GDF2 (BMP9), GDF3 (VGR-2), IGF1, JAG1
Cell-Cell Communication
DHH, DLL1 (DELTA1), GJA1 (CX43), GJB1 (CX32), GJB2 (CX26), JAG1
Cell Adhesion Molecules
APC, BGLAP, CD4, CD44, CDH1 (E-Cadherin), CDH2 (N-Cadherin), COL9A1, CTNNA1, CXCL12 (SDF1), NCAM1
Metabolic Markers
ABCG2 (BCRP), ALDH1A1 (RALDH1), ALDH2, FGFR1
Stem Cell Differentiation Markers
Embryonic Cell Lineage Markers
ACTC1, ASCL2, FOXA2 (HNF3B), ISL1, KRT15, MSX1, MYOD1, PDX1, TBXT (Brachyury)
Hematopoietic Cell Lineage Markers
CD3D, CD4, CD8A, CD8B, MME
Mesenchymal Cell Lineage Markers
ACAN, ALPI, BGLAP, COL1A1, COL2A1, COL9A1, PPARG
Neural Cell Lineage Markers
CD44, NCAM1, S100B, SIGMAR1, TUBB3
Signaling Pathways Important for Stem Cell Maintenance
Notch Signaling
DLL1 (DELTA1), DLL3, DTX1, DTX2, DVL1, EP300, HDAC2, JAG1, KAT2A, NOTCH1, NOTCH2, NUMB
WNT Signaling
ADAR, APC, AXIN1, BTRC (bTrCP), CCND1, FRAT1, FZD1, MYC, PPARD, WNT1