Target List
Stress Responses
Inflammatory Response
CCL2 (MCP-1), CCL5 (RANTES), CCR1, CCR2, IL1R1, IL1R2, ITGB2, NFKB1, NOS3 (eNOS), SELE, SPP1, TNF
Oxidative Stress Response
APOE, CCL5 (RANTES), SOD1
Response to Pests, Pathogens or Parasites
CCL2 (MCP-1), CCR2, CSF2 (GM-CSF), FN1, IL4, ITGB2, TNF
Response to Virus
CCL5 (RANTES), IFNAR2, TNF
Response to Wounding
CCN2, CCR1, CCR2, FN1, PDGFB, TNF, VWF
Other Stress Response Genes
IFNG, PPARG, VEGFA
Apoptosis
Anti-Apoptotic
BCL2, BCL2A1 (BFL1), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC3 (c-IAP2), CCL2 (MCP-1), CFLAR (CASPER), FAS, IL1A, IL2, NFKB1, SERPINB2 (PAI-2), SPP1, TGFB1, TNF, TNFAIP3
Induction of Apoptosis
APOE, BAX, BID, CFLAR (CASPER), FAS
Other Apoptosis Genes
IL5, ITGB2
Blood Coagulation & Circulation
Blood Coagulation
FGA, ITGA2, LPA, SERPINE1 (PAI-1)
Circulation
APOA1, APOB, APOE, COL3A1, ELN, ENG (EVI-1), LPA, LPL, NPY
Platelet Activation
PDGFA, PDGFB, PDGFRB, VWF
Regulation of Blood Pressure
ACE, FGA
Cell Adhesion Molecules
Cell-Cell Adhesion
CD44, CDH5, ICAM1, ITGB2, SELE, SELL (LECAM-1), TNF, VCAM1, VEGFA
Cell-Extracellular Matrix (ECM) Adhesion
CD44, ITGA2, ITGA5, ITGAX, ITGB2, SPP1
Other Cell Adhesion Molecules
CCL2 (MCP-1), CCL5 (RANTES), CCN2, CCR1, ELN, ENG (EVI-1), FN1, LAMA1, SELPLG (P-Selectin), THBS4, TNC, VWF
Extracellular Matrix (ECM) Molecules
Extracellular Matrix (ECM) Protease Inhibitors
LPA, SERPINB2 (PAI-2), SERPINE1 (PAI-1)
Extracellular Matrix (ECM) Proteases
ACE, MMP1, MMP3
Extracellular Matrix (ECM) Structural Constituents
COL3A1, ELN, FN1
Other Extracellular Matrix (ECM) Molecules
APOA1, APOB, APOE, CCL2 (MCP-1), CCL5 (RANTES), CCN2, CSF2 (GM-CSF), FGA, FGF2 (BFGF), HBEGF, IFNAR2, IFNG, IL1A, IL2, IL3, IL4, IL5, LAMA1, LIF, LPL, NPY, PDGFA, PDGFB, PLIN2, SPP1, THBS4, TNC, VEGFA, VWF
Lipid Transport & Metabolism
Cholesterol Metabolism
ABCA1, APOA1, APOB, APOE, IL4, LDLR
Fatty Acid Metabolism
FABP3, LPL, PPARA, PTGS1 (COX1)
Lipid Transport
ABCA1, APOA1, APOB, APOE, FABP3, LDLR, LPA, LPL, MSR1
Lipoprotein Metabolism
APOA1, APOE, LDLR, LPL
Steroid Metabolism
NR1H3, PPARA, PPARD, PPARG, RXRA
Other Lipid Metabolism Genes
APOE, LPA, PLIN2
Cell Growth & Proliferation
Growth Factors & Receptors
CSF2 (GM-CSF), KDR (VEGFR3), PDGFRB, SPP1
Negative Regulation of Cell Proliferation
BCL2, FABP3, IL1A
Positive Regulation of Cell Proliferation
CSF1 (MCSF), FGA, FGF2 (BFGF), HBEGF, IL2, IL3, IL5, LIF, VEGFA
Regulation of the Cell Cycle
FGF2 (BFGF), IL1A, PDGFA, PDGFB, TGFB1, TGFB2, VEGFA
Other Cell Growth & Proliferation Genes
CCN2, ELN, IFNG, IL4, NPY
Transcriptional Regulation
Nuclear Receptors
NR1H3, PPARA, PPARD, PPARG, RXRA
Other Transcription Regulators
EGR1, KLF2, NFKB1, TNF, TNFAIP3