Target List
Conduction of Pain
Ion Channels
TRPA1, TRPV1, TRPV3
Sodium Channels
SCN10A, SCN11A, SCN3A, SCN9A, SLC6A2
Potassium Channels
KCNIP3, KCNJ6, KCNQ2, KCNQ3
Purinergic (P2Y) Receptors
ADORA1, P2RX3, P2RX4, P2RX7, P2RY1
Opioid Receptors
OPRD1, OPRK1, OPRM1
Cannabinoid Receptors
CNR1, CNR2
Synaptic Transmission
Glutamate Receptors
GRIN1, GRIN2B, GRM1, GRM5
Serotonin (5-Hydroxytryptamine) Receptors
HTR1A, HTR2A
Calcium Channels
CACNA1B
Pain Response Modulation
Eicosanoid Metabolism
PLA2G1B, PTGER1, PTGER3, PTGER4, PTGES, PTGES2, PTGES3, PTGS1 (COX1), PTGS2 (COX2)
Inflammation
ACE, ALOX5, BDKRB1, CALCA, CCK, CCKBR, CCL2 (MCP-1), CCR2, CD200, CD4, CHRNA4, CSF1 (MCSF), CX3CR1, DBH, EDN1, EDNRA, FAAH, GCH1, IL10, IL18, IL1A, IL1B, IL2, IL6, ITGAM, ITGB2, MAPK1 (ERK2), MAPK14 (p38ALPHA), MAPK3 (ERK1), MAPK8 (JNK1), PENK, PNOC, PROK2, TAC1, TACR1, TLR2, TLR4, TNF
Neurotransmitters
ADRB2, COMT, DBH, MAOB, PDYN, PENK, PNOC
Neurotrophins
BDNF, GDNF, NGF, NTRK1