Details
| Type | Protein Coding |
| Official Symbol | Sry |
| Official Name | sex determining region Y [Source:RGD Symbol;Acc:3759] |
| Ensembl ID | ENSRNOG00000062090 |
| Bio databases IDs | |
| Aliases | sex determining region Y |
| Synonyms | LOC103694545, sex determining region of Chr Y, sex determining region Y, Sry3B, SRYGENE, Tdf, Tdy |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sry often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- high mobility group (HMG)-box domain superfamily
- enzyme binding
- DNA bending protein
- transcription factor binding
- protein binding
- glutamine-rich domain
- sequence-specific DNA binding
- DNA binding
- RNA polymerase II transcription factor activity, sequence-specific DNA binding
- HMG-like domain
- HMG (high mobility group) box
- HMG-box domain
- high mobility group
- glutamine repeat domain
- histidine glutamine rich domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neuroinflammation
- motor dysfunction
phenotypes
- 46 XY gonadal dysgenesis
role in cell
- expression in
- activation in
- growth
- signaling in
- proliferation
- invasiveness
- tumorigenicity
- degeneration
- degradation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- chromatin