Nrn1 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Involved in nervous system development. Is active in postsynaptic endocytic zone. Orthologous to human NRN1 (neuritin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nrn1 |
| Official Name | neuritin 1 [Source:RGD Symbol;Acc:621586] |
| Ensembl ID | ENSRNOG00000050767 |
| Bio databases IDs | |
| Aliases | neuritin 1 |
| Synonyms | 0710008J23Rik, Cpg15, dJ380B8.2, Neuritin, neuritin 1, NRN |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nrn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neuritin protein family
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastatic colorectal cancer
- septic shock
- Alzheimer disease
- depressive disorder
- epileptic seizure
role in cell
- expression in
- branching
- branching in
- morphology
- growth
- formation in
- recruitment in
- quantity
- growth in
- survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- cytoskeleton
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nrn1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- synapse
- extracellular region
- plasma membrane