Tpsab1 Gene Summary [Rat]
Predicted to enable identical protein binding activity and serine-type endopeptidase activity. Predicted to be involved in extracellular matrix disassembly and proteolysis. Predicted to be located in mast cell granule. Predicted to be active in extracellular space. Orthologous to several human genes including TPSD1 (tryptase delta 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tpsab1 |
| Official Name | tryptase alpha/beta 1 [Source:RGD Symbol;Acc:3066] |
| Ensembl ID | ENSRNOG00000024181 |
| Bio databases IDs | |
| Aliases | tryptase alpha/beta 1 |
| Synonyms | Mast cell tryptase, Mcpt7, rMCP-7, TPSB1, tryptase alpha/beta 1, tryptase α/β 1 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tpsab1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- peptidase
- identical protein binding
Pathways
Biological processes and signaling networks where the Tpsab1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- lysosome
- secretory granules