QuantiNova LNA PCR Focus Panel Human PI3K-AKT Signaling Pathway | GeneGlobe

Product Specification

Target List

AKT & PI3 Kinase Family Members & Their Regulators

AKT1AKT2AKT3BTKGRB10GRB2HSPB1 (HSP27)ILKMTCP1PDK2PDPK1PIK3CA (p110-alpha)PIK3CGPIK3R1 (p85-ALPHA)PIK3R2 (p85-BETA)PAK1PRKCAPRKCBPRKCZPTENTCL1A

IGF-1 Signaling

CSNK2A1ELK1FOSGRB2HRASIGF1IGF1RIRS1JUNMAP2K1MAPK3 (ERK1)MAPK8 (JNK1)PTPN11RAF1RASA1SHC1SOS1SRF

GSK3 Inactivation & β-Catenin Accumulation

ADARAKT1APCCCND1CD14CTNNB1EIF2AK2GJA1 (CX43)GSK3BIRAK1MYD88NFKB1PDK1TIRAPTLR4TOLLIP

Cytoskeleton Regulators

CDC42PDGFRARAC1RHOAWASL

PTEN-Dependent Cell Cycle Arrest & Apoptosis

AKT1CDKN1B (P27KIP1)FASLG (TNFSF6)FOXO3GRB2ILKITGB1MAPK1 (ERK2)MAPK3 (ERK1)PDK1PDK2PTENPTK2 (FAK)RBL2SHC1SOS1

BAD Phosphorylation & Anti-Apoptotic Pathways

AKT1BADGRB2HRASIGF1RIRS1MAP2K1MAPK1 (ERK2)MAPK3 (ERK1)RAF1RPS6KA1SHC1SOS1YWHAH

mTOR Signaling

AKT1EIF4BEIF4EEIF4EBP1 (4E-BP1)EIF4G1FKBP1A (FKBP12)MTORPDK1PDK2PTENRHEBRPS6KB1TSC1TSC2

Regulation of eIF4e & p70 S6 Kinases

AKT1EIF4EEIF4EBP1 (4E-BP1)EIF4G1MTORIRS1MAPK1 (ERK2)MAPK14 (p38ALPHA)MAPK3 (ERK1)PABPC1PDK1PDK2PRKCAPTEN

Regulation of Adipogenesis

Other AKT Signaling Genes

CASP9CHUK (IKKα)FOXO1NFKBIA (IκBα, MAD3)

Product Resources

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Array Layout for PCR Plates

File Size: 153.59 KBLanguage: English

Array Layout for Rotor-Gene Q

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