ENOPH1 Gene Summary [Human]
Enables acireductone synthase activity. Involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ENOPH1 |
| Official Name | enolase-phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:24599] |
| Ensembl ID | ENSG00000145293 |
| Bio databases IDs | |
| Aliases | enolase-phosphatase 1, Enolase-phosphatase E1, acireductone synthase |
| Synonyms | 2310057D15Rik, BB183658, E1, E-1 ENZYME, enolase-phosphatase 1, MASA, MST145, mtnC, RGD1309016 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ENOPH1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HAD hydrolase, family IA, variant 1
- acireductone synthase
- enzyme
- protein binding
- 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
- Haloacid Dehalogenase-like Hydrolases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ENOPH1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- L-methionine salvage from methylthioadenosine
- L-methionine biosynthetic process from S-adenosylmethionine
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
- 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
- protein binding
- acireductone synthase activity