S100a7a Gene Summary [Mouse]
Enables chemoattractant activity. Acts upstream of or within inflammatory response. Located in extracellular space. Is expressed in central nervous system. Used to study psoriasis. Orthologous to human S100A7 (S100 calcium binding protein A7); S100A7L2 (S100 calcium binding protein A7 like 2); and S100A7A (S100 calcium binding protein A7A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | S100a7a |
| Official Name | S100 calcium binding protein A7A [Source:MGI Symbol;Acc:MGI:2687194] |
| Ensembl ID | ENSMUSG00000063767 |
| Bio databases IDs | |
| Aliases | S100 calcium binding protein A7A |
| Synonyms | Gm1020, LOC686730, S100a15, S100a15a, S100a17l1, S100a7, S100a7a15, S100A7f, S100A7L1, S100 calcium binding protein A7A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse S100a7a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- S-100/ICaBP type calcium binding domain
- chemoattractant
- EF hand
- calcium ion binding
- EFh
- protein binding
- receptor binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Nucleus
- Endoplasmic Reticulum
- cytosol